Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4284633 | 0.92 | KMT2A (0.49) | SLC40A1PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL5265199 | 0.88 | GAA (0.47) | KMT2AALDH1A1SMN1; SMN2MEN1KDM4E | |
| SCHEMBL5266751 | 0.87 | ALDH1A1 (0.46) | KMT2AALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL5267213 | 0.87 | ALDH1A1 (0.45) | KMT2AALDH1A1HTTMEN1KDM4E | |
| SCHEMBL5265268 | 0.87 | KCNA5 (0.46) | KMT2AALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL5270408 | 0.86 | LMNA (0.49) | ALDH1A1HTTSMN1; SMN2LMNACYP2C9 | |
| SCHEMBL5270764 | 0.85 | KMT2A (0.52) | KMT2AALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL5269789 | 0.85 | MEN1 (0.51) | KMT2AALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL5269858 | 0.85 | KMT2A (0.45) | KMT2AALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL5271482 | 0.84 | MCL1 (0.42) | SLC40A1KMT2AALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |