Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.64 |
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | NCF1 | P14598 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | COMT | P21964 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 8-Hydroxy Quinaldine SCHEMBL29483489 | 0.78 | METAP2 (1.00) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| 8-Hydroxy Quinaldine SCHEMBL297247 | 0.78 | METAP2 (1.00) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL3230745 | 0.78 | METAP2 (0.58) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL672744 | 0.77 | METAP2 (0.63) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL30082244 | 0.77 | METAP2 (0.63) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL21767732 | 0.77 | METAP2 (0.63) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| 8-Hydroxy Quinaldine SCHEMBL4286984 | 0.77 | METAP2 (0.96) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| 8-Hydroxy Quinaldine SCHEMBL5089361 | 0.77 | METAP2 (0.96) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| 8-Hydroxy Quinaldine SCHEMBL4762935 | 0.77 | METAP2 (0.96) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| 8-Hydroxy Quinaldine SCHEMBL22734876 | 0.77 | METAP2 (0.96) | METAP2PLAUNCF1ALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9241957-B2 | Compositions and methods for reducing photosensitivity associated with photodynamic therapy | DUSA PHARMACEUTICALS, INC. (US) | 2016-01-26 | — | — | US | claimed |
| US-20140316491-A1 | COMPOSITIONS AND METHODS FOR REDUCING PHOTOSENSITIVITY ASSOCIATED WITH PHOTODYNAMIC THERAPY | DUSA PHARMACEUTICALS, INC. (US) | 2014-10-23 | — | — | US | claimed |
| US-8609073-B2 | Compositions and methods for reducing photosensitivity associated with photodynamic therapy | DUSA PHARMACEUTICALS, INC. (US) | 2013-12-17 | — | — | US | claimed |
| US-20090123400-A1 | COMPOSITIONS AND METHODS FOR REDUCING PHOTOSENSITIVITY ASSOCIATED WITH PHOTODYNAMIC THERAPY | DUSA PHARMACEUTICALS, INC. | 2009-05-14 | — | — | US | claimed |
| WO-2006096492-A2 | COMPOSITIONS AND METHODS FOR REDUCING PHOTOSENSITIVITY ASSOCIATED WITH PHOTODYNAMIC THERAPY | DUSA PHARMACEUTICALS, INC. (US) | 2006-09-14 | — | — | WO | claimed |
| US-9241957-B2 | Compositions and methods for reducing photosensitivity associated with photodynamic therapy | DUSA PHARMACEUTICALS, INC. (US) | 2016-01-26 | — | — | US | disclosed |
| US-20140316491-A1 | COMPOSITIONS AND METHODS FOR REDUCING PHOTOSENSITIVITY ASSOCIATED WITH PHOTODYNAMIC THERAPY | DUSA PHARMACEUTICALS, INC. (US) | 2014-10-23 | — | — | US | disclosed |
| US-8609073-B2 | Compositions and methods for reducing photosensitivity associated with photodynamic therapy | DUSA PHARMACEUTICALS, INC. (US) | 2013-12-17 | — | — | US | disclosed |
| US-20090123400-A1 | COMPOSITIONS AND METHODS FOR REDUCING PHOTOSENSITIVITY ASSOCIATED WITH PHOTODYNAMIC THERAPY | DUSA PHARMACEUTICALS, INC. | 2009-05-14 | — | — | US | disclosed |
| WO-2006096492-A2 | COMPOSITIONS AND METHODS FOR REDUCING PHOTOSENSITIVITY ASSOCIATED WITH PHOTODYNAMIC THERAPY | DUSA PHARMACEUTICALS, INC. (US) | 2006-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140316491-A1 | COMPOSITIONS AND METHODS FOR REDUCING PHOTOSENSITIVITY ASSOCIATED WITH PHOTODYNAMIC THERAPY | PPOX, TYR, HCCS | METAP2 730/4885PLAU 899/4885NCF1 1316/4885 |
| US-20090123400-A1 | COMPOSITIONS AND METHODS FOR REDUCING PHOTOSENSITIVITY ASSOCIATED WITH PHOTODYNAMIC THERAPY | PPOX, TYR, HCCS | METAP2 730/4885PLAU 899/4885NCF1 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.