Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | MGLL | Q99685 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4297245 | 0.95 | CYP19A1 (0.35) | ALOX5CYP19A1KDM4ELMNACYP2C19 | |
| SCHEMBL4284253 | 0.71 | PTGS1 (0.37) | PTGS1KDM4ELMNACYP2C19ALDH1A1 | |
| SCHEMBL5597442 | 0.69 | CRBN (0.41) | KDM4ELMNACYP2C19TSHRNPSR1 | |
| SCHEMBL11499230 | 0.68 | ALOX5 (0.47) | ALOX5PTGS1PTGS2MGLLFAAH | |
| SCHEMBL26289325 | 0.67 | MGLL (0.38) | ALOX5PTGS1PTGS2MGLLFAAH | |
| SCHEMBL461664 | 0.67 | CRBN (0.45) | ALOX5PTGS1PTGS2MGLLFAAH | |
| SCHEMBL26459349 | 0.67 | ALOX5 (0.50) | ALOX5PTGS1PTGS2MGLLFAAH | |
| Succinimide SCHEMBL7039031 | 0.66 | CRBN (0.61) | ALOX5CYP19A1KDM4ELMNACYP2C19 | |
| Succinimide SCHEMBL27423831 | 0.66 | CRBN (0.61) | ALOX5CYP19A1KDM4ELMNACYP2C19 | |
| SCHEMBL6228568 | 0.66 | ALOX5 (0.45) | ALOX5PTGS1PTGS2MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009157938-A1 | A2B ADENOSINE RECEPTOR ANTAGONISTS FOR TREATING CANCER | CV THERAPEUTICS, INC. (US) | 2009-12-30 | — | — | WO | disclosed |