SCHEMBL4286

SCHEMBL4286

Brc1cccc(Oc2ccccc2)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 4/20 0.46
F10 P00742 4/20 0.46
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
ST14 Q9Y5Y6 1/20 0.46
HTT P42858 2/20 0.44
ALDH1A1 P00352 1/20 0.44
LTA4H P09960 1/20 0.44
TSHR P16473 1/20 0.44
MAP4K4 O95819 1/20 0.44
HTR7 P34969 1/20 0.43
CYP1A2 P05177 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
MAPK1 P28482 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31026898 1.00 F2 (0.46) F2F10PRSS1PRSS2PRSS3
SCHEMBL2521152 0.87 LTA4H (0.58) F2F10PRSS1PRSS2PRSS3
SCHEMBL9268808 0.82 MEN1 (0.47) F2F10PRSS1PRSS2PRSS3
SCHEMBL10980485 0.82 HTT (0.47) F2F10PRSS1PRSS2PRSS3
SCHEMBL10985855 0.82 L3MBTL1 (0.50) F2F10PRSS1PRSS2PRSS3
SCHEMBL10566124 0.81 F2 (0.41) F2F10PRSS1PRSS2PRSS3
SCHEMBL19965079 0.80 LMNA (0.55) HTTALDH1A1LTA4HMAP4K4SMN1; SMN2
SCHEMBL8941674 0.79 F2 (0.46) F2F10PRSS1PRSS2PRSS3
SCHEMBL16511926 0.78 F2 (0.48) F2F10PRSS1PRSS2PRSS3
SCHEMBL21580746 0.77 HTR7 (0.42) F2F10ALDH1A1HTR7CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118647270-A Novel derivatives of non-coding amino acids and their use as herbicides 福提费斯特有限公司 2024-09-13 CN claimed
WO-2023131951-A1 NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES FORTEPHEST LTD. (IL) 2023-07-13 WO claimed
JP-58018360-A None JP disclosed
JP-59029664-A None JP disclosed
CN-118647270-A Novel derivatives of non-coding amino acids and their use as herbicides 福提费斯特有限公司 2024-09-13 CN disclosed
US-20240284907-A1 NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES FORTEPHEST LTD. (IL) 2024-08-29 US disclosed
WO-2023131951-A1 NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES FORTEPHEST LTD. (IL) 2023-07-13 WO disclosed
US-9796677-B2 Amide compound and pharmaceutical comprising same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2017-10-24 US disclosed
EP-2483251-B1 POLYCYCLIC COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AMIRA PHARMACEUTICALS INC (US) 2016-10-26 EP disclosed
EP-2483251-B1 POLYCYCLIC COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AMIRA PHARMACEUTICALS INC (US) 2016-10-26 EP disclosed
EP-3081556-A1 AMIDE COMPOUND AND PHARMACEUTICAL COMPRISING SAME Japan Science and Technology Agency (JP) 2016-10-19 EP disclosed
US-5223536-A Pyrethroid-like pesticides FMC CORPORATION (US) 1993-06-29 US disclosed
WO-1993001715-A1 1,4-DIARYL-1-CYCLOPROPYL-4-SUBSTITUTED BUTANES AS INSECTICIDES AND ACARICIDES FMC CORPORATION (US) 1993-02-04 WO disclosed
US-4694013-A Insecticidal and acaricidal phenoxypyrdinyl esters and intermediates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-09-15 US disclosed
CN-86108309-A The phenoxypyridines base ester and the intermediate thereof that are used for desinsection and kill mite 1987-06-17 CN disclosed
EP-0223521-A2 Insecticidal and acaricidal phenoxypyridinyl esters and intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-05-27 EP disclosed
US-4499275-A PESTICIDES; INSECTICIDES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1985-02-12 US disclosed
JP-S5929664-A PREPARATION OF 6-PHENOXYPICOLINALDEHYDE NISSAN CHEM IND LTD 1984-02-16 JP disclosed
US-4393213-A Process for producing 6-phenoxypicolinic aldehydes NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1983-07-12 US disclosed
JP-S5818360-A PREPARATION OF 2-BROMO-6-PHENOXYPYRIDINE NISSAN CHEM IND LTD 1983-02-02 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240284907-A1 NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES DDT, DDC, GLUL F2 4784/4885F10 4788/4885PRSS1 3674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.