Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4285493 | 0.83 | LMNA (0.36) | L3MBTL1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL4292395 | 0.81 | ALDH1A1 (0.47) | KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4284239 | 0.80 | L3MBTL1 (0.38) | L3MBTL1P2RY12PIK3CDKMT2ANPC1 | |
| SCHEMBL4290844 | 0.79 | PIK3CD (0.35) | L3MBTL1P2RY12PIK3CDKMT2ANPC1 | |
| SCHEMBL4297276 | 0.78 | PARP1 (0.51) | KMT2ANPC1RAB9A | |
| SCHEMBL4286066 | 0.77 | RAB9A (0.35) | L3MBTL1P2RY12PIK3CDRAB9AKDM4E | |
| SCHEMBL4288567 | 0.75 | FAAH (0.34) | P2RY12KMT2A | |
| SCHEMBL4291155 | 0.75 | SMN1; SMN2 (0.38) | L3MBTL1P2RY12RAB9AKDM4EALDH1A1 | |
| SCHEMBL4292598 | 0.75 | PDE4B (0.37) | P2RY12PIK3CDKMT2ANPC1RAB9A | |
| SCHEMBL4292720 | 0.74 | GAA (0.34) | L3MBTL1PIK3CDKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | L3MBTL1 3597/4885P2RY12 2069/4885PIK3CD 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.