Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Mercaptopyridine SCHEMBL9500219 | 0.86 | LMNA (0.52) | LMNANAPRTP4HTML3MBTL1NPC1 | |
| 2-Mercaptopyridine SCHEMBL11327454 | 0.82 | ALDH1A1 (0.52) | LMNANAPRTP4HTML3MBTL1NPC1 | |
| 2-Mercaptopyridine SCHEMBL27619077 | 0.81 | KDM4E (0.43) | LMNANAPRTP4HTML3MBTL1NPC1 | |
| 2-Mercaptopyridine SCHEMBL29276656 | 0.81 | KDM4E (0.48) | LMNANAPRTP4HTML3MBTL1NPC1 | |
| Dipyridyl SCHEMBL28487455 | 0.80 | KDM4E (0.58) | LMNANAPRTP4HTML3MBTL1NPC1 | |
| 2-Mercaptopyridine SCHEMBL28322234 | 0.79 | CES2 (0.41) | LMNANAPRTP4HTML3MBTL1NPC1 | |
| 2-Mercaptopyridine SCHEMBL54576 | 0.78 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL17686493 | 0.77 | THRB (0.44) | LMNAL3MBTL1NPC1RAB9AKDM4E | |
| Acrylic Acid SCHEMBL1302201 | 0.77 | KMT2A (0.50) | LMNANAPRTP4HTML3MBTL1NPC1 | |
| 2-Aminopyridine SCHEMBL9490439 | 0.77 | NOS3 (0.61) | LMNANAPRTP4HTML3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163599-A1 | Mif adsorbant | FRAUNHOFER-GESELLSCHAFT ZUR FORDERUND DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2009-06-25 | — | — | US | disclosed |