Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10723443 | 0.83 | GAA (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL148782 | 0.81 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL181945 | 0.78 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL5864262 | 0.78 | GAA (0.43) | GAAMGAMSIMGAM2ALDH1A1 | |
| Methylene Chloride SCHEMBL3176439 | 0.78 | GAA (0.43) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7841654 | 0.77 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1339430 | 0.77 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2706813 | 0.76 | ALDH1A1 (0.45) | ALDH1A1EGLN1LMNAHMGCRCHRM1 | |
| SCHEMBL8820595 | 0.76 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL17305098 | 0.75 | HMGCR (0.62) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849086-B | Hydrophily chain junctor and its application on drug molecule and cell-binding molecules conjugation reaction | 杭州多禧生物科技有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-105849086-A | Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules | 杭州多禧生物科技有限公司 | 2016-08-10 | — | — | CN | disclosed |
| US-8344115-B2 | Immunoassay for specific determination of S-adenosylmethionine and analogs thereof in biological samples | HAO, XIUJUAN | 2013-01-01 | — | — | US | disclosed |
| WO-2009131643-A1 | IMMUNOASSAY FOR SPECIFIC DETERMINATION OF S-ADENOSYMETHIONINE AND ANALOGS THEREOF IN BIOLOGICAL SAMPLES | MONABIO, INC. (US) | 2009-10-29 | — | — | WO | disclosed |
| US-20090263879-A1 | Immunoassay for specific determination of S-adenosylmethionine and analogs thereof in biological samples | HAO, XIUJUAN | 2009-10-22 | — | — | US | disclosed |
| US-7342005-B2 | Antibiotic compounds | ASTRAZENECA UK LIMITED (GB) | 2008-03-11 | — | — | US | disclosed |
| US-7101895-B2 | Cyclohexyl sulphone derivatives as gamma-secretase inhibitors | MERCK SHARP & DOHME LIMITED (GB) | 2006-09-05 | — | — | US | disclosed |
| US-7041836-B2 | Antibiotic compounds | ASTRAZENECA UK LIMITED (GB) | 2006-05-09 | — | — | US | disclosed |
| US-20050209212-A1 | Antibiotic compounds | ASTRAZENECA UK LIMITED | 2005-09-22 | — | — | US | disclosed |
| US-20040122050-A1 | Cyclohexyl sulphone derivatives as gamma-secretase inhibitors | MERCK SHARP & DOHME LTD. (GB) | 2004-06-24 | — | — | US | disclosed |
| EP-0291234-B1 | Peptidic human leukocyte elastase (HLE) inhibitors | ZENECA INC (US) | 1994-03-23 | — | — | EP | disclosed |
| EP-0579826-A1 | CARBAPENEMS CONTAINING A CARBOXY SUBSTITUTED PHENYL GROUP, PROCESSES FOR THEIR PREPARATION, INTERMEDIATES AND USE AS ANTIBIOTICS | ZENECA LIMITED (GB) | 1994-01-26 | — | — | EP | disclosed |
| EP-0577210-A1 | A method of preparing a magenta development inhibitor releasing coupler | EASTMAN KODAK COMPANY (US) | 1994-01-05 | — | — | EP | disclosed |
| US-5270301-A | Fluoro-amide derivatives | ICI AMERICAS INC. (US) | 1993-12-14 | — | — | US | disclosed |
| WO-1993015078-A1 | CARBAPENEMS CONTAINING A CARBOXY SUBSTITUTED PHENYL GROUP, PROCESSES FOR THEIR PREPARATION, INTERMEDIATES AND USE AS ANTIBIOTICS | ZENECA LIMITED (GB) | 1993-08-05 | — | — | WO | disclosed |
| EP-0540118-A1 | Photographic material and process | EASTMAN KODAK COMPANY (US) | 1993-05-05 | — | — | EP | disclosed |
| US-5164371-A | HETEROCYCLIC KETONES | ICI AMERICAS INC. (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0399688-A1 | Trifluoroketopeptide derivatives useful as human leukocyte elastase inhibitors | ZENECA INC. (US) | 1990-11-28 | — | — | EP | disclosed |
| EP-0397427-A1 | Fluoro-amide derivatives having human leucocyte elastase inhibiting activity | ZENECA INC. (US) | 1990-11-14 | — | — | EP | disclosed |
| EP-0291234-A2 | Peptidic human leukocyte elastase (HLE) inhibitors | ZENECA INC. (US) | 1988-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122050-A1 | Cyclohexyl sulphone derivatives as gamma-secretase inhibitors | BACE1, BACE2, APP | GAA 194/4885MGAM 2822/4885SI 196/4885 |
| US-20090263879-A1 | Immunoassay for specific determination of S-adenosylmethionine and analogs thereof in biological samples | AHCY, MAT2A, MAT1A | GAA 1019/4885MGAM 426/4885SI 165/4885 |
| US-20050209212-A1 | Antibiotic compounds | NRDC, NPR3, NGLY1 | GAA 2694/4885MGAM 214/4885SI 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.