Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289539 | 0.80 | MAPT (0.46) | — | |
| SCHEMBL13624920 | 0.77 | POLB (0.59) | — | |
| SCHEMBL13624707 | 0.74 | KDM4E (0.48) | HTR2A | |
| SCHEMBL6483085 | 0.72 | CYP19A1 (1.00) | CYP19A1HTR2A | |
| SCHEMBL9826632 | 0.70 | CYP19A1 (0.86) | CYP19A1 | |
| SCHEMBL29543480 | 0.68 | TAAR1 (0.56) | HTR2A | |
| SCHEMBL14655775 | 0.68 | TAAR1 (0.56) | HTR2A | |
| SCHEMBL8570365 | 0.68 | PKM (0.47) | — | |
| SCHEMBL9826783 | 0.67 | CYP19A1 (0.86) | CYP19A1 | |
| SCHEMBL1164083 | 0.67 | MAOB (0.95) | CYP19A1MAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275664-A1 | NOVEL POLYAMINE ANALOG CONJUGATES AND QUINONE CONJUGATES AS THERAPIES FOR CANCERS AND PROSTATE DISEASES | PROGEN PHARMACEUTICALS, INC. | 2009-11-05 | — | — | US | disclosed |
| US-20090275664-A1 | NOVEL POLYAMINE ANALOG CONJUGATES AND QUINONE CONJUGATES AS THERAPIES FOR CANCERS AND PROSTATE DISEASES | PROGEN PHARMACEUTICALS, INC. | 2009-11-05 | — | — | US | disclosed |
| US-20080194697-A1 | NOVEL POLYAMINE ANALOG CONJUGATES AND QUINONE CONJUGATES AS THERAPIES FOR CANCERS AND PROSTATE DISEASES | CELLGATE, INC. | 2008-08-14 | — | — | US | disclosed |
| US-20080194697-A1 | NOVEL POLYAMINE ANALOG CONJUGATES AND QUINONE CONJUGATES AS THERAPIES FOR CANCERS AND PROSTATE DISEASES | CELLGATE, INC. | 2008-08-14 | — | — | US | disclosed |
| US-7279502-B2 | Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases | CELLGATE, INC. (US) | 2007-10-09 | — | — | US | disclosed |
| US-7279502-B2 | Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases | CELLGATE, INC. (US) | 2007-10-09 | — | — | US | disclosed |
| US-7253207-B2 | Quinones as disease therapies | CELLGATE, INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-20050233943-A1 | Novel polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases | CELLGATE, INC. | 2005-10-20 | — | — | US | disclosed |
| EP-1574507-A2 | Furo- and pyrano-naphthoquinones and their use in the treatment of cancer | SLIL Biomedical Corporation (US) | 2005-09-14 | — | — | EP | disclosed |
| EP-1185493-B1 | QUINONES FOR TREATMENT OF DISEASES | SLIL BIOMEDICAL CORP (US) | 2005-07-20 | — | — | EP | disclosed |
| US-6809176-B2 | Quinones as disease therapies | SLIL BIOMEDICAL, CORPORATION | 2004-10-26 | — | — | US | disclosed |
| US-20040006049-A1 | Novel polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases | SLIL BIOMEDICAL CORPORATION (US) | 2004-01-08 | — | — | US | disclosed |
| US-6649587-B1 | Cytostatic or cytocidal componenet conjugated to a polypeptide recognized and cleaved by enzymes such as prostate specific antigen (PSA) and cathepsin B | SLIL BIOMEDICAL CORPORATION | 2003-11-18 | — | — | US | disclosed |
| US-20030013677-A1 | QUINONES AS DISEASE THERAPIES | CELLGATE, INC. | 2003-01-16 | — | — | US | disclosed |
| US-20020183512-A1 | Novel quinones as disease therapies | SLIL BIOMEDICAL CORPORATION | 2002-12-05 | — | — | US | disclosed |
| US-6482943-B1 | Quinones as disease therapies | SLIL BIOMEDICAL CORPORATION | 2002-11-19 | — | — | US | disclosed |
| EP-1185493-A1 | QUINONES FOR TREATMENT OF DISEASES | SLIL Biomedical Corporation (US) | 2002-03-13 | — | — | EP | disclosed |
| EP-1173223-A2 | CONJUGATES AS THERAPIES FOR CANCERS AND PROSTATE DISEASES | Slil Biomedical Corporation (US) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000066175-A2 | CONJUGATES AS THERAPIES FOR CANCER AND PROSTATE DISEASES | SLIL BIOMEDICAL CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |
| WO-2000066528-A2 | QUINONES FOR TREATMENT OF DISEASES | SLIL BIOMEDICAL CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006049-A1 | Novel polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases | CTSB, CTSL, CTSV | CYP19A1 977/4885MAOB 93/4885HTR2A 3822/4885 |
| US-20030013677-A1 | QUINONES AS DISEASE THERAPIES | NQO1, NDUFV2, SDHB | CYP19A1 469/4885MAOB 774/4885HTR2A 4628/4885 |
| US-20080194697-A1 | NOVEL POLYAMINE ANALOG CONJUGATES AND QUINONE CONJUGATES AS THERAPIES FOR CANCERS AND PROSTATE DISEASES | CTSB, KLK3, FOLH1 | CYP19A1 941/4885MAOB 96/4885HTR2A 3706/4885 |
| US-20050233943-A1 | Novel polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases | CTSB, CTSL, CTSV | CYP19A1 977/4885MAOB 93/4885HTR2A 3822/4885 |
| US-20020183512-A1 | Novel quinones as disease therapies | NQO1, NDUFV2, SDHB | CYP19A1 593/4885MAOB 761/4885HTR2A 4631/4885 |
| US-20090275664-A1 | NOVEL POLYAMINE ANALOG CONJUGATES AND QUINONE CONJUGATES AS THERAPIES FOR CANCERS AND PROSTATE DISEASES | CTSB, CTSL, CTSV | CYP19A1 977/4885MAOB 93/4885HTR2A 3822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.