SCHEMBL4290842

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4295123	0.88	HSD17B14 (0.50)	HSD17B14HTR3EHTR3BHTR3AHTR3D
	SCHEMBL4300878	0.81	PROKR1 (0.46)	HSD17B14HTR3EHTR3BHTR3AHTR3D
	SCHEMBL4292208	0.81	SCD5 (0.48)	HSD17B14HTR3EHTR3BHTR3AHTR3D
	SCHEMBL4292214	0.81	SCD5 (0.48)	HSD17B14HTR3EHTR3BHTR3AHTR3D
	SCHEMBL4301528	0.81	SCD5 (0.53)	HSD17B14PROKR1SCD5SCD
	SCHEMBL7893494	0.79	SCD5 (0.46)	HSD17B14HTR3EHTR3BHTR3AHTR3D
	SCHEMBL4301974	0.78	HSD17B14 (0.51)	HSD17B14HTR3EHTR3BHTR3AHTR3D
	SCHEMBL4306219	0.78	HCRTR1 (0.45)	HSD17B14PRKCQ
	SCHEMBL4306226	0.78	HCRTR1 (0.45)	HSD17B14PRKCQ
	SCHEMBL4299601	0.77	PRKCQ (0.44)	HSD17B14PRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.