Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | HCN1 | O60741 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4272978 | 0.78 | KDM4E (0.35) | ALDH1A1CHRM1KDM4ESMOLMNA | |
| SCHEMBL4273950 | 0.76 | MAPK1 (0.36) | ALDH1A1CHRM1KDM4EHRH4 | |
| SCHEMBL4280380 | 0.72 | OPRM1 (0.47) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL4283420 | 0.71 | SLC6A3 (0.40) | ALDH1A1LMNA | |
| SCHEMBL3408526 | 0.65 | BDKRB1 (0.49) | ALDH1A1HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL4132978 | 0.65 | SIGMAR1 (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28275217 | 0.64 | KMT2A (0.52) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL18390251 | 0.63 | CHRM1 (0.74) | HSD17B10CHRM1RAB9A | |
| SCHEMBL13271645 | 0.61 | HSD17B10 (0.61) | ALDH1A1HSD17B10CHRM1KDM4E | |
| SCHEMBL4119403 | 0.60 | CARM1 (0.41) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | ALDH1A1 863/4885HSD17B10 2254/4885CHRM1 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.