Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.67 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6392968 | 0.86 | MITF (0.69) | MITFALDH1A1POLBMAPK1HTT | |
| SCHEMBL4440400 | 0.85 | NPC1 (0.56) | GPR35MITFALDH1A1POLBMAPK1 | |
| SCHEMBL22588908 | 0.84 | CA12 (0.72) | MITFALDH1A1POLBMAPK1HTT | |
| SCHEMBL8006359 | 0.84 | HPGD (0.66) | ALDH1A1HPGDRAB9APTPN11TGM2 | |
| SCHEMBL7525010 | 0.83 | ALDH1A1 (0.69) | MITFALDH1A1POLBMAPK1HTT | |
| SCHEMBL12888865 | 0.83 | MAPK1 (0.65) | MITFALDH1A1POLBMAPK1HTT | |
| SCHEMBL4089354 | 0.83 | MITF (0.65) | MITFALDH1A1POLBMAPK1HTT | |
| SCHEMBL22543145 | 0.81 | NR1H4 (0.78) | MITFALDH1A1POLBMAPK1HTT | |
| SCHEMBL11400184 | 0.81 | GPR35 (1.00) | GPR35MAPTPTPN11MEN1KMT2A | |
| SCHEMBL22732031 | 0.79 | TGM2 (0.74) | MITFALDH1A1POLBMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275047-A1 | CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLATE CYCLASE | SAALAU-BETHELL SUSANNE MARIA | 2009-11-05 | — | — | US | disclosed |
| EP-1904629-A2 | CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLATE CYCLASE | Astex Therapeutics Limited (GB) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007010285-A2 | CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLATE CYCLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-01-25 | — | — | WO | disclosed |