Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | MITF | O75030 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6392968 | 0.86 | MITF (0.69) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL22588908 | 0.84 | CA12 (0.72) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL4292376 | 0.83 | GPR35 (0.67) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL4089354 | 0.83 | MITF (0.65) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL12888865 | 0.83 | MAPK1 (0.65) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL22543145 | 0.81 | NR1H4 (0.78) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL11161409 | 0.79 | GPR35 (0.58) | ALDH1A1POLBHTTMAPTRAB9A | |
| SCHEMBL22732031 | 0.79 | TGM2 (0.74) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL11748157 | 0.79 | MTNR1B (0.68) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL7932214 | 0.79 | ALDH1A1 (0.73) | ALDH1A1MITFPOLBMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183246-A1 | TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071527-A1 | TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (DE) | 2000-11-30 | — | — | WO | disclosed |