SCHEMBL429746

SCHEMBL429746

CCC(CN)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 2/20 0.55
GABBR1 Q9UBS5 2/20 0.55
TAAR1 Q96RJ0 6/20 0.54
HTR2A P28223 2/20 0.54
LMNA P02545 1/20 0.48
CHRNB2 P17787 1/20 0.45
CHRNA4 P43681 1/20 0.45
HRH1 P35367 1/20 0.44
CCR5 P51681 1/20 0.44
CYP2D6 P10635 1/20 0.44
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL429745 1.00 GABBR2 (0.55) GABBR2GABBR1TAAR1HTR2ALMNA
SCHEMBL2344157 1.00 GABBR2 (0.55) GABBR2GABBR1TAAR1HTR2ALMNA
Hydrochloric Acid SCHEMBL2346631 0.98 GABBR2 (0.53) GABBR2GABBR1TAAR1HTR2ALMNA
SCHEMBL17906514 0.87 CHRNB2 (0.59) GABBR2GABBR1TAAR1HTR2ACHRNB2
Methylamine SCHEMBL27931105 0.85 LMNA (0.52) GABBR2GABBR1TAAR1HTR2ALMNA
SCHEMBL1539105 0.85 TAAR1 (0.65) GABBR2GABBR1TAAR1HTR2ACHRNB2
SCHEMBL169508 0.85 LMNA (0.56) TAAR1HTR2ALMNAHRH1CCR5
Hydrochloric Acid SCHEMBL10676327 0.82 TAAR1 (0.62) GABBR2GABBR1TAAR1HTR2ACHRNB2
Ammonia Solution, Strong SCHEMBL1640901 0.82 LMNA (0.54) TAAR1HTR2ALMNAHRH1CCR5
SCHEMBL19734403 0.82 GABBR2 (0.52) GABBR2GABBR1TAAR1HTR2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119233997-A Tetrahedral antibodies 生物分子控股有限责任公司 2024-12-31 CN claimed
EP-4463485-A2 TETRAHEDRAL ANTIBODIES Biomolecular Holdings LLC (US) 2024-11-20 EP claimed
US-20230364224-A1 Pharmaceutical Composition For Allergen Specific Immunotherapy HOPITAUX UNIVERSITAIRES DE GENEVE (CH) 2023-11-16 US claimed
EP-4213873-A1 COMPOSITE SOLDER BALLS METALLISED ON THE SURFACE AND CALIBRATED FOR THE ASSEMBLY OF ELECTRONIC BOARDS Hopitaux Universitaires de Genève (CH) 2023-07-26 EP claimed
WO-2023137373-A1 TETRAHEDRAL ANTIBODIES BIOMOLECULAR HOLDINGS LLC (US) 2023-07-20 WO claimed
WO-2023137387-A2 TETRAHEDRAL ANTIBODIES BIOMOLECULAR HOLDINGS LLC (US) 2023-07-20 WO claimed
US-20230220115-A1 TETRAHEDRAL ANTIBODIES BIOMOLECULAR HOLDINGS LLC (US) 2023-07-13 US claimed
US-20230220116-A1 TETRAHEDRAL ANTIBODIES BIOMOLECULAR HOLDINGS LLC (US) 2023-07-13 US claimed
EP-4178615-A1 TETRAHEDRAL ANTIBODIES Biomolecular Holdings LLC (US) 2023-05-17 EP claimed
WO-2022058432-A1 PHARMACEUTICAL COMPOSITION FOR ALLERGEN SPECIFIC IMMUNOTHERAPY Hôpitaux Universitaires de Genève (CH) 2022-03-24 WO claimed
EP-2655314-A1 MULTI- API LOADING PRODRUGS Alkermes Pharma Ireland Limited (IE) 2013-10-30 EP claimed
US-20130184265-A1 Prodrugs of Secondary Amine Compounds ALKERMES PHARMA IRELAND LIMITED (IE) 2013-07-18 US claimed
WO-2013088255-A1 PRODRUGS OF SECONDARY AMINE COMPOUNDS ALKERMES PHARMA IRELAND LIMITED (IE) 2013-06-20 WO claimed
WO-2012088441-A1 MULTI- API LOADING PRODRUGS ALKERMES, INC. (US) 2012-06-28 WO claimed
CN-1343024-A Organic amine used as additive in electrochemical battery MERCK PATENT GMBH (DE) 2002-04-03 CN claimed
EP-1187244-A2 Organic amines as additives for electrochemical cells MERCK PATENT GmbH (DE) 2002-03-13 EP claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-4995997-A Containing aromatic amine YUSHIRO CHEMICAL INDUSTRY CO., LTD. (JP) 1991-02-26 US claimed
EP-0388320-A1 Antibacterial water-soluble cutting fluids resistant to yeast-like fungi YUSHIRO CHEMICAL INDUSTRY CO. LTD. (JP) 1990-09-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230220115-A1 TETRAHEDRAL ANTIBODIES FCGR3B, FCGR2A, FCGR1A GABBR2 3094/4885GABBR1 3474/4885TAAR1 3652/4885
US-20230220116-A1 TETRAHEDRAL ANTIBODIES FCGR3B, FCGR2A, FCGR1A GABBR2 3094/4885GABBR1 3474/4885TAAR1 3652/4885
US-20130184265-A1 Prodrugs of Secondary Amine Compounds HNMT, MAOB, UGT1A1 GABBR2 1127/4885GABBR1 791/4885TAAR1 125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.