Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302201 | 0.91 | PPARA (0.47) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL4299382 | 0.91 | L3MBTL1 (0.43) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4308419 | 0.90 | KMT2A (0.42) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL4302845 | 0.88 | PPARA (0.47) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| Methoxymethane SCHEMBL5317742 | 0.83 | CFD (0.46) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| Methoxymethane SCHEMBL5319099 | 0.82 | CFD (0.45) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| Methoxymethane SCHEMBL5317331 | 0.82 | PPARA (0.47) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| Methoxymethane SCHEMBL5317705 | 0.81 | KMT2A (0.45) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL3419319 | 0.81 | KDM4C (0.50) | MTNR1AMTNR1BMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5316326 | 0.81 | CFD (0.46) | MAPTALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110060156-A1 | Pyruvate Derivatives with Neuroprotective Effect, Process for Preparing the Same and Pharmaceutical Composition Comprising the Same | S.H. PHARMA., LTD. (KR) | 2011-03-10 | — | — | US | claimed |
| WO-2009108017-A2 | NEW PYRUVATE DERIVATIVES WITH NEUROPROTECTIVE EFFECT, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | S.H. PHARMA., LTD (KR) | 2009-09-03 | — | — | WO | claimed |
| US-20110060156-A1 | Pyruvate Derivatives with Neuroprotective Effect, Process for Preparing the Same and Pharmaceutical Composition Comprising the Same | S.H. PHARMA., LTD. (KR) | 2011-03-10 | — | — | US | disclosed |
| WO-2009108017-A2 | NEW PYRUVATE DERIVATIVES WITH NEUROPROTECTIVE EFFECT, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | S.H. PHARMA., LTD (KR) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110060156-A1 | Pyruvate Derivatives with Neuroprotective Effect, Process for Preparing the Same and Pharmaceutical Composition Comprising the Same | PC, PDK1, PDK2 | MTNR1A 1946/4885MTNR1B 2022/4885MAPT 155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.