Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302845 | 0.97 | PPARA (0.47) | PPARAFAAHL3MBTL1MEN1KMT2A | |
| SCHEMBL4299382 | 0.91 | L3MBTL1 (0.43) | PPARAL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL4298649 | 0.91 | MTNR1A (0.46) | L3MBTL1MEN1KMT2ANPC1MAPT | |
| SCHEMBL4308419 | 0.90 | KMT2A (0.42) | PPARAMEN1KMT2ANPC1MAPT | |
| Methoxymethane SCHEMBL5317331 | 0.89 | PPARA (0.47) | PPARAFAAHL3MBTL1MEN1KMT2A | |
| Methoxymethane SCHEMBL5318378 | 0.86 | PPARA (0.47) | PPARAFAAHL3MBTL1MEN1KMT2A | |
| SCHEMBL5317330 | 0.81 | FAAH (0.44) | PPARAFAAHL3MBTL1MEN1KMT2A | |
| Methoxymethane SCHEMBL5317742 | 0.81 | CFD (0.46) | L3MBTL1MEN1KMT2ANPC1MAPT | |
| SCHEMBL5316326 | 0.81 | CFD (0.46) | PPARAMEN1KMT2ANPC1MAPT | |
| SCHEMBL4305586 | 0.81 | MRGPRX4 (0.47) | MEN1KMT2ANPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110060156-A1 | Pyruvate Derivatives with Neuroprotective Effect, Process for Preparing the Same and Pharmaceutical Composition Comprising the Same | S.H. PHARMA., LTD. (KR) | 2011-03-10 | — | — | US | claimed |
| WO-2009108017-A2 | NEW PYRUVATE DERIVATIVES WITH NEUROPROTECTIVE EFFECT, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | S.H. PHARMA., LTD (KR) | 2009-09-03 | — | — | WO | claimed |
| US-20110060156-A1 | Pyruvate Derivatives with Neuroprotective Effect, Process for Preparing the Same and Pharmaceutical Composition Comprising the Same | S.H. PHARMA., LTD. (KR) | 2011-03-10 | — | — | US | disclosed |
| WO-2009108017-A2 | NEW PYRUVATE DERIVATIVES WITH NEUROPROTECTIVE EFFECT, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | S.H. PHARMA., LTD (KR) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110060156-A1 | Pyruvate Derivatives with Neuroprotective Effect, Process for Preparing the Same and Pharmaceutical Composition Comprising the Same | PC, PDK1, PDK2 | PPARA 111/4885FAAH 3881/4885L3MBTL1 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.