SCHEMBL429980

SCHEMBL429980

CC(C)(C)c1ccc2c(c1)C(C)(C)c1cc(B3OC(C)(C)C(C)(C)O3)ccc1-2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.41
LPL P06858 13/20 0.38
LIPG Q9Y5X9 13/20 0.38
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
FFAR1 O14842 1/20 0.34
CA12 O43570 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
F11 P03951 1/20 0.33
BACE1 P56817 1/20 0.32
BACE2 Q9Y5Z0 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10295966 0.95 LIPG (0.42) HIF1ALPLLIPGCA1CA2
SCHEMBL13098391 0.91 HIF1A (0.41) HIF1ALPLLIPGCA1CA2
SCHEMBL69358 0.87 LIPG (0.47) LPLLIPGCA1CA2CA9
SCHEMBL12865795 0.86 HIF1A (0.40) HIF1ALPLLIPGCA1CA2
SCHEMBL15298702 0.85 LIPG (0.40) HIF1ALPLLIPGALDH1A1
SCHEMBL16435209 0.84 LIPG (0.44) LPLLIPGCA1CA2CA9
SCHEMBL13648561 0.83 HIF1A (0.42) HIF1ALPLLIPGCA1CA2
SCHEMBL13308814 0.82 HIF1A (0.34) HIF1ALPLLIPG
SCHEMBL1753517 0.81 LIPG (0.50) LPLLIPGCA1CA2CA9
SCHEMBL21970457 0.80 ALDH1A1 (0.44) CA1CA2CA9CA12NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9812646-B2 Organic compound and organic light-emitting device and display apparatus having the same CANON KABUSHIKI KAISHA (JP) 2017-11-07 US disclosed
US-9812646-B2 Organic compound and organic light-emitting device and display apparatus having the same CANON KABUSHIKI KAISHA (JP) 2017-11-07 US disclosed
EP-2903958-B1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS HAVING THE SAME CANON KK (JP) 2017-08-30 EP disclosed
US-9240553-B2 Indeno[1,2-b]phenanthrene compound and organic light emitting element including the same CANON KABUSHIKI KAISHA (JP) 2016-01-19 US disclosed
US-9240553-B2 Indeno[1,2-b]phenanthrene compound and organic light emitting element including the same CANON KABUSHIKI KAISHA (JP) 2016-01-19 US disclosed
US-20150333267-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2015-11-19 US disclosed
US-20150333267-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2015-11-19 US disclosed
US-20150255727-A1 INDENO[1,2-b]PHENANTHRENE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2015-09-10 US disclosed
US-20150255727-A1 INDENO[1,2-b]PHENANTHRENE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2015-09-10 US disclosed
US-8841004-B2 Binaphthyl compound and organic light emitting element using the same CANON KABUSHIKI KAISHA (JP) 2014-09-23 US disclosed
US-7883786-B2 highly efficient and highly luminescent optical power and is superior in durability CANON KABUSHIKI KAISHA (JP) 2011-02-08 US disclosed
US-7883786-B2 highly efficient and highly luminescent optical power and is superior in durability CANON KABUSHIKI KAISHA (JP) 2011-02-08 US disclosed
EP-2045231-B1 Binaphthyl compound and organic light emitting element using the same CANON KK (JP) 2010-07-21 EP disclosed
US-20090200919-A1 FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE CANON KABUSHIKI KAISHA (JP) 2009-08-13 US disclosed
US-20090200919-A1 FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE CANON KABUSHIKI KAISHA (JP) 2009-08-13 US disclosed
US-20090091252-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2009-04-09 US disclosed
US-20090091252-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2009-04-09 US disclosed
EP-2045231-A1 Binaphthyl compound and organic light emitting element using the same Canon Kabushiki Kaisha (JP) 2009-04-08 EP disclosed
US-20080297034-A1 BIPHENYL DERIVATIVE AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME CANON KABUSHIKI KAISHA (JP) 2008-12-04 US disclosed
US-20080297034-A1 BIPHENYL DERIVATIVE AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME CANON KABUSHIKI KAISHA (JP) 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090091252-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME ALPL, MT-ND4L, LAGE3 HIF1A 4402/4885LPL 1254/4885LIPG 2208/4885
US-20080297034-A1 BIPHENYL DERIVATIVE AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME LEF1, CYP1B1, ESR1 HIF1A 2858/4885LPL 1927/4885LIPG 3067/4885
US-20150255727-A1 INDENO[1,2-b]PHENANTHRENE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT INCLUDING THE SAME CYP1A1, CYP1B1, AHR HIF1A 664/4885LPL 4472/4885LIPG 4695/4885
US-20090200919-A1 FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE AFF1, LEF1, AFF2 HIF1A 3564/4885LPL 1917/4885LIPG 2072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.