Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434969 | 0.91 | CA4 (0.54) | CA1CA2CA7CA9CA12 | |
| SCHEMBL136229 | 0.91 | CA4 (0.54) | CA1CA2CA7CA9CA12 | |
| SCHEMBL8784562 | 0.84 | CA1 (0.58) | CA1CA2CA7CA9CA12 | |
| SCHEMBL7617149 | 0.80 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL29634970 | 0.80 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL6546972 | 0.80 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL12227837 | 0.78 | CA1 (0.65) | CA1CA2CA7CA9CA12 | |
| SCHEMBL30676990 | 0.78 | CA1 (0.65) | CA1CA2CA7CA9CA12 | |
| SCHEMBL2150628 | 0.77 | CA1 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL8784660 | 0.77 | CA4 (0.54) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030065-A1 | FLUORESCEIN POLYMER CONJUGATES | ISI LIFE SCIENCES, INC. (US) | 2018-02-01 | — | — | US | claimed |
| WO-2015053980-A1 | PREPARATION OF ORGANOPHOSPHATE PEPTIDE ADDUCTS | BATTELLE MEMORIAL INSTITUTE (US) | 2015-04-16 | — | — | WO | claimed |
| US-20150099864-A1 | PREPARATION OF ORGANOPHOSPHATE PEPTIDE ADDUCTS | BATTELLE MEMORIAL INSTITUTE | 2015-04-09 | — | — | US | claimed |
| US-5990300-A | REACTING NUCLEOSIDE HAVING UNPROTECTED 3' HYDROXY GROUP WITH NUCLEOSIDE 5'-TRIPHOSPHATE HAVING 3' POSITION PROTECTED WITH REMOVABLE BLOCKING MOIETY, IN PRESENCE OF ENZYME WHICH CATALYZES FORMATION OF 5' TO 3' PHOSPHODIESTER LINKAGE | Hiatt, Andrew C. (US) | 1999-11-23 | — | — | US | claimed |
| EP-4320138-B1 | PSEUDO SOLID PHASE PROTECTING GROUP AND METHODS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES AND OLIGONUCLEOTIDE CONJUGATES | BACHEM AG (CH) | 2026-04-01 | — | — | EP | disclosed |
| US-20250282813-A1 | PSEUDO SOLID PHASE PROTECTING GROUP AND METHODS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES AND OLIGONUCLEOTIDE CONJUGATES | BACHEM HOLDING AG (CH) | 2025-09-11 | — | — | US | disclosed |
| US-20250179110-A1 | IMPROVED OLIGONUCLEOTIDE SYNTHESIS | BACHEM HOLDING AG (CH) | 2025-06-05 | — | — | US | disclosed |
| CN-117836304-A | Improved oligonucleotide synthesis | 巴克姆股份公司 | 2024-04-05 | — | — | CN | disclosed |
| EP-4320138-A1 | PSEUDO SOLID PHASE PROTECTING GROUP AND METHODS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES AND OLIGONUCLEOTIDE CONJUGATES | Bachem Holding AG (CH) | 2024-02-14 | — | — | EP | disclosed |
| EP-3645548-B1 | METHODS FOR PREPARING BILE ACIDS | MEDYTOX INC (KR) | 2023-11-29 | — | — | EP | disclosed |
| EP-4276104-A2 | IMPROVED OLIGONUCLEOTIDE SYNTHESIS SUPPRESSING DEPURINATION | Bachem Holding AG (CH) | 2023-11-15 | — | — | EP | disclosed |
| EP-4161942-B1 | IMPROVED OLIGONUCLEOTIDE SYNTHESIS SUPPRESSING DEPURINATION | BACHEM HOLDING AG (CH) | 2023-08-02 | — | — | EP | disclosed |
| EP-1412346-B1 | METHOD FOR PRODUCING NOVEL SPINOSYN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2005-03-09 | — | — | EP | disclosed |
| EP-1412346-A1 | METHOD FOR PRODUCING NOVEL SPINOSYN DERIVATIVES | Bayer CropScience AG (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003010155-A1 | METHOD FOR PRODUCING NOVEL SPINOSYN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2003-02-06 | — | — | WO | disclosed |
| US-6232465-B1 | NUCLEOTIDE 5'-TRIPHOSPHATE HAVING A REMOVABLE BLOCKING MOIETY PROTECTING THE 3' POSITION AND LINKED TO THE 3' CARBON WHICH IS A HYDROCARBYL, SO A SINGLE PHOSPHODIESTER LINKAGE IS FORMED BETWEEN THE INITIATING SUBSTRATE AND 5' NUCLEOTIDE | Hiatt, Andrew C. | 2001-05-15 | — | — | US | disclosed |
| US-6214987-B1 | MIXTURE OF A TEMPLATE-INDEPENDENT ENZYME AND A 3' BLOCKED NUCLEOTIDE 5'-TRIPHOSPHATE; EFFICIENT SYNTHESIS OF OLIGO- AND POLYNUCLEOTIDES | Hiatt, Andrew C. | 2001-04-10 | — | — | US | disclosed |
| US-5872244-A | STEPWISE CREATION OF PHOSPHODIESTER BONDS BETWEEN DESIRED NUCLEOSIDES RESULTING IN THE SYNTHESIS OF POLYNUCLEOTIDES HAVING A PREDETERMINED NUCLEOTIDE SEQUENCE | Hiatt, Andrew C. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5808045-A | Compositions for enzyme catalyzed template-independent creation of phosphodiester bonds using protected nucleotides | Hiatt, Andrew C. (US) | 1998-09-15 | — | — | US | disclosed |
| US-5763594-A | DNA AND NUCLEOSIDE-5-TRIPHOSPHATE WITH REMOVABLE BLOCKING GROUPS | Hiatt, Andrew C. (US) | 1998-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180030065-A1 | FLUORESCEIN POLYMER CONJUGATES | PFAS, CD44, FGB | CA1 1673/4885CA2 2448/4885CA7 224/4885 |
| US-20250179110-A1 | IMPROVED OLIGONUCLEOTIDE SYNTHESIS | POLRMT, FBL, RNGTT | CA1 3033/4885CA2 4662/4885CA7 3514/4885 |
| US-20250282813-A1 | PSEUDO SOLID PHASE PROTECTING GROUP AND METHODS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES AND OLIGONUCLEOTIDE CONJUGATES | POLR2H, POLR2E, SUB1 | CA1 2035/4885CA2 3537/4885CA7 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.