Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.36 |
| ▸ | FAAH | O00519 | 5/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.30 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30003370 | 0.75 | MGLL (0.40) | MGLLFAAHBCHETLR9HSP90AA1 | |
| SCHEMBL28755760 | 0.72 | BCHE (0.42) | MGLLFAAHBCHETLR9HSP90AA1 | |
| SCHEMBL327660 | 0.67 | TLR9 (0.40) | MGLLFAAHBCHETLR9HSP90AA1 | |
| SCHEMBL28682497 | 0.62 | — | — | |
| SCHEMBL4344306 | 0.61 | BCHE (0.43) | MGLLFAAHBCHETLR9HSP90AA1 | |
| SCHEMBL349418 | 0.61 | MGLL (0.50) | MGLLFAAHBCHETLR9HSP90AA1 | |
| SCHEMBL31179957 | 0.60 | MGLL (0.56) | MGLLFAAHBCHEHSP90AA1CCR6 | |
| SCHEMBL28796586 | 0.58 | CDC25B (0.30) | — | |
| SCHEMBL9418751 | 0.58 | HSP90AA1 (0.56) | MGLLFAAHBCHETLR9HSP90AA1 | |
| SCHEMBL5178729 | 0.57 | MGLL (0.48) | MGLLFAAHBCHETLR9HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11850216-B2 | 18F labeling of proteins using sortases | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-12-26 | — | — | US | disclosed |
| US-20200384137-A1 | 18F LABELING OF PROTEINS USING SORTASES | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2020-12-10 | — | — | US | disclosed |
| US-10556024-B2 | 18F labeling of proteins using sortases | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2020-02-11 | — | — | US | disclosed |
| US-10434197-B2 | Tetrazine-trans-cyclooctene ligation for the rapid construction of radionuclide labeled probes | UNIVERSITY OF DELAWARE (US) | 2019-10-08 | — | — | US | disclosed |
| US-9999689-B2 | Imaging beta cell mass | THE GENERAL HOSPITAL CORPORATION (US) | 2018-06-19 | — | — | US | disclosed |
| US-20160368993-A1 | ALPHA-V BETA-6 INTEGRIN-BINDING ANTIBODY FRAGMENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-12-22 | — | — | US | disclosed |
| US-20160287734-A1 | 18F LABELING OF PROTEINS USING SORTASES | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2016-10-06 | — | — | US | disclosed |
| US-20160263250-A1 | Imaging Beta Cell Mass | THE GENERAL HOSPITAL CORPORATION | 2016-09-15 | — | — | US | disclosed |
| EP-2595967-B1 | TETRAZINE-TRANS-CYCLOOCTENE LIGATION FOR THE RAPID CONSTRUCTION OF RADIONUCLIDE LABELED PROBES | UNIV DELAWARE (US) | 2016-03-23 | — | — | EP | disclosed |
| CN-103221398-B | For the tetrazine-trans cyclooctene ligation of rapid build radioisotope labeling probe | UNIVERSITY OF DELAWARE (US) | 2016-03-23 | — | — | CN | disclosed |
| US-9289516-B2 | Imaging beta cell mass | THE GENERAL HOSPITAL CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| WO-2015073746-A9 | 18F LABELING OF PROTEINS USING SORTASES | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2015-07-23 | — | — | WO | disclosed |
| WO-2015085179-A1 | ALPHA-V BETA-6 INTEGRIN-BINDING ANTIBODY FRAGMENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-06-11 | — | — | WO | disclosed |
| WO-2015073746-A2 | 18F LABELING OF PROTEINS USING SORTASES | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2015-05-21 | — | — | WO | disclosed |
| US-20140056812-A1 | Imaging Beta Cell Mass | THE GENERAL HOSPITAL CORPORATION (US) | 2014-02-27 | — | — | US | disclosed |
| US-20130266512-A1 | Tetrazine-trans-cyclooctene Ligation for the Rapid Construction of Radionuclide Labeled Probes | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-10-10 | — | — | US | disclosed |
| CN-103221398-A | Tetrazine-trans-yclooctene ligation for the rapid construction of radionuclide labeled probes | UNIV DELAWARE | 2013-07-24 | — | — | CN | disclosed |
| EP-2595967-A2 | TETRAZINE-TRANS-CYCLOOCTENE LIGATION FOR THE RAPID CONSTRUCTION OF RADIONUCLIDE LABELED PROBES | University Of Delaware (US) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012121746-A2 | IMAGING BETA CELL MASS | THE GENERAL HOSPITAL CORPORATION (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012012612-A2 | TETRAZINE-TRANS-CYCLOOCTENE LIGATION FOR THE RAPID CONSTRUCTION OF RADIONUCLIDE LABELED PROBES | UNIVERSITY OF DELAWARE (US) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11850216-B2 | 18F labeling of proteins using sortases | SORT1, ANPEP, SPG11 | MGLL 1097/4885FAAH 2818/4885BCHE 1863/4885 |
| US-20160287734-A1 | 18F LABELING OF PROTEINS USING SORTASES | SORT1, ANPEP, SPG11 | MGLL 1142/4885FAAH 2740/4885BCHE 1824/4885 |
| US-20140056812-A1 | Imaging Beta Cell Mass | IAPP, GLP1R, GPR119 | MGLL 1193/4885FAAH 2620/4885BCHE 525/4885 |
| US-10434197-B2 | Tetrazine-trans-cyclooctene ligation for the rapid construction of radionuclide labeled probes | TTL, TALDO1, TTI1 | MGLL 2081/4885FAAH 2480/4885BCHE 1310/4885 |
| US-20200384137-A1 | 18F LABELING OF PROTEINS USING SORTASES | SORT1, ANPEP, SPG11 | MGLL 1097/4885FAAH 2818/4885BCHE 1863/4885 |
| US-20130266512-A1 | Tetrazine-trans-cyclooctene Ligation for the Rapid Construction of Radionuclide Labeled Probes | TTL, TALDO1, TTI1 | MGLL 2081/4885FAAH 2480/4885BCHE 1310/4885 |
| US-10556024-B2 | 18F labeling of proteins using sortases | SORT1, ANPEP, SPG11 | MGLL 1142/4885FAAH 2740/4885BCHE 1824/4885 |
| US-20160263250-A1 | Imaging Beta Cell Mass | IAPP, GLP1R, GPR119 | MGLL 1193/4885FAAH 2620/4885BCHE 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.