SCHEMBL4302806

SCHEMBL4302806

O=C(O)CCCCCCC(SSC(CCCCCCC(=O)O)N1C(=O)CCC1=O)N1C(=O)CCC1=O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
TSHR P16473 1/20 0.39
NFKB1 P19838 1/20 0.39
PMP22 Q01453 1/20 0.39
GSTK1 Q9Y2Q3 2/20 0.39
PTGER4 P35408 7/20 0.38
PTGER3 P43115 6/20 0.38
PTGER2 P43116 5/20 0.38
FFAR4 Q5NUL3 1/20 0.38
FFAR1 O14842 1/20 0.38
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37
PTGS1 P23219 4/20 0.37
PTGS2 P35354 4/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL826505 1.00 LMNA (0.39) LMNATSHRNFKB1PMP22GSTK1
SCHEMBL825651 1.00 LMNA (0.39) LMNATSHRNFKB1PMP22GSTK1
SCHEMBL4310967 0.98 GSTK1 (0.37) LMNATSHRNFKB1PMP22GSTK1
SCHEMBL846234 0.79 ALDH1A1 (0.47) LMNATSHRNFKB1PMP22GSTK1
SCHEMBL17821007 0.79 ALDH1A1 (0.47) LMNATSHRNFKB1PMP22GSTK1
SCHEMBL30773222 0.77 ALDH1A1 (0.49) LMNATSHRNFKB1PMP22GSTK1
SCHEMBL9607 0.75 KMT2A (0.43) KMT2AALDH1A1
Octanedioate SCHEMBL7080168 0.73 TSHR (0.55) LMNATSHRNFKB1PMP22FFAR4
SCHEMBL15475975 0.72 PTGS1 (0.45) LMNAGSTK1PTGER4PTGER3PTGER2
SCHEMBL16460504 0.72 ALDH1A1 (0.35) LMNATSHRNFKB1PMP22GSTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200038427-A1 CYCLIC NUCLEIC ACID MOLECULE HAVING GENE EXPRESSION CONTROL FUNCTION BONAC CORPORATION (JP) 2020-02-06 US disclosed
EP-3604528-A1 CYCLIC NUCLEIC ACID MOLECULE HAVING GENE EXPRESSION CONTROL FUNCTION Bonac Corporation (JP) 2020-02-05 EP disclosed
WO-2009066080-A2 ARRAY NANOBIODESIGN LIMITED (GB) 2009-05-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200038427-A1 CYCLIC NUCLEIC ACID MOLECULE HAVING GENE EXPRESSION CONTROL FUNCTION RNMT, RNGTT, SRRT LMNA 1101/4885TSHR 1664/4885NFKB1 2145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.