Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.46 |
| ▸ | HPGD | P15428 | 8/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 4/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20943509 | 0.78 | DYRK1A (0.49) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL20980460 | 0.75 | KDM4E (0.38) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL20980454 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL10806894 | 0.74 | PDE10A (0.35) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL11047934 | 0.69 | DYRK1A (0.37) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL11105911 | 0.68 | PTGS1 (0.46) | ALDH1A1KDM4EHPGDGLARAB9A | |
| SCHEMBL362977 | 0.67 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL24659083 | 0.67 | DYRK1A (0.38) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL1104802 | 0.67 | DYRK1A (0.45) | ALDH1A1KDM4EDYRK1ARAB9ANPC1 | |
| SCHEMBL17269120 | 0.67 | NPC1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140033-A | SUPPORT WITH SILVER HALIDE EMULSIONS WITH COUPLERS | EASTMAN KODAK COMPANY (US) | 2000-10-31 | — | — | US | claimed |
| EP-1014185-A1 | Photographic element, pyrazolazole coupler, method for it's preparation and an azomethine dye | EASTMAN KODAK COMPANY (US) | 2000-06-28 | — | — | EP | claimed |
| US-20170092877-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. | 2017-03-30 | — | — | US | disclosed |
| US-20110112106-A1 | TRICYCLIC INHIBITORS OF 5-LIPOXYGENASE | AMIRA PHARMACEUTICALS, INC. (US) | 2011-05-12 | — | — | US | disclosed |
| US-7919621-B2 | Tricyclic inhibitors of 5-lipoxygenase | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-05 | — | — | US | disclosed |
| JP-2009286869-A | DYE COMPOUND AND INK CONTAINING THE DYE COMPOUND | CANON INC | 2009-12-10 | — | — | JP | disclosed |
| US-20080009498-A1 | Phosphodiesterase inhibitors and nitric oxide donors, compositions and methods of use | NITROMED, INC. (US) | 2008-01-10 | — | — | US | disclosed |
| US-20070173508-A1 | TRICYCLIC INHIBITORS OF 5-LIPOXYGENASE | AMIRA PHARMACEUTICALS, INC. (US) | 2007-07-26 | — | — | US | disclosed |
| US-20060063774-A1 | Phosphodiesterase inhibitor compounds and nitric oxide donors | GARVEY DAVID S | 2006-03-23 | — | — | US | disclosed |
| EP-1109543-A4 | NITROSATED AND NITROSYLATED PHOSPHODIESTERASE INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED INC (US) | 2006-03-08 | — | — | EP | disclosed |
| US-6930113-B2 | Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use | NITROMED, INC. (US) | 2005-08-16 | — | — | US | disclosed |
| US-4596806-A | 7-piperidino-1,2,3,5-tetrahydroimidazo[2,1-b]-quinazolin-2-one having platelet aggregation inhibitory activity | DAIICHI SEIYAKU CO., LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| EP-0133234-A2 | Imidazoquinazolin-2-one compounds process for their production and pharmaceutical compositions containing said compounds | DAIICHI SEIYAKU CO., LTD. (JP) | 1985-02-20 | — | — | EP | disclosed |
| EP-0129258-A1 | Imidazoquinazoline compound | DAIICHI SEIYAKU CO., LTD. (JP) | 1984-12-27 | — | — | EP | disclosed |
| EP-0008408-B1 | 1,2,3,5-TETRAHYDROIMIDAZOTHIENOPYRIMIDIN-2-ONES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | DAIICHI SEIYAKU CO., LTD. (JP) | 1981-12-09 | — | — | EP | disclosed |
| US-4284773-A | ANTICOAGULANTS | DAIICHI SEIYAKU CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| US-4228167-A | Diuretic and vasodilating tricyclic quinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4228167-A | Diuretic and vasodilating tricyclic quinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-10-14 | — | — | US | disclosed |
| EP-0008408-A1 | 1,2,3,5-Tetrahydroimidazothienopyrimidin-2-ones, a process for their preparation and pharmaceutical compositions | DAIICHI SEIYAKU CO., LTD. (JP) | 1980-03-05 | — | — | EP | disclosed |
| US-4179560-A | Imidazo- and pyrimido[2,1-b]quinazolines and preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173508-A1 | TRICYCLIC INHIBITORS OF 5-LIPOXYGENASE | ALOX5, ALOX15, ALOX15B | ALDH1A1 802/4885KDM4E 2132/4885HPGD 69/4885 |
| US-20110112106-A1 | TRICYCLIC INHIBITORS OF 5-LIPOXYGENASE | ALOX5, ALOX15, ALOX15B | ALDH1A1 802/4885KDM4E 2132/4885HPGD 69/4885 |
| US-20080009498-A1 | Phosphodiesterase inhibitors and nitric oxide donors, compositions and methods of use | PDE3A, PDE3B, PDE2A | ALDH1A1 1344/4885KDM4E 1851/4885HPGD 64/4885 |
| US-20170092877-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | PPOX, EPCAM, STOM | ALDH1A1 1724/4885KDM4E 2892/4885HPGD 2698/4885 |
| US-20060063774-A1 | Phosphodiesterase inhibitor compounds and nitric oxide donors | PDE3B, PDE3A, PDE5A | ALDH1A1 256/4885KDM4E 1496/4885HPGD 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.