Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053403 | 0.82 | LMNA (0.39) | LMNATSHR | |
| SCHEMBL13227921 | 0.81 | THRB (0.31) | — | |
| SCHEMBL27599533 | 0.79 | THRB (0.35) | — | |
| SCHEMBL16589114 | 0.78 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL18017012 | 0.77 | THRB (0.39) | — | |
| SCHEMBL18017021 | 0.77 | THRB (0.39) | — | |
| SCHEMBL18017019 | 0.77 | THRB (0.39) | — | |
| SCHEMBL18017014 | 0.77 | THRB (0.39) | — | |
| SCHEMBL18017024 | 0.77 | THRB (0.39) | — | |
| SCHEMBL18017015 | 0.77 | THRB (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922836-B1 | NEW NUCLEOPHILE-REACTIVE SULFONATED COMPOUNDS FOR THE (RADIO)LABELLING OF (BIO)MOLECULES; PRECURSORS AND CONJUGATES THEREOF | ADVANCED ACCELERATOR APPLICATIONS (FR) | 2019-07-10 | — | — | EP | disclosed |
| US-20190119316-A1 | NEW NUCLEOPHILE-REACTIVE SULFONATED COMPOUNDS FOR THE (RADIO)LABELLING OF (BIO)MOLECULES; PRECURSORS AND CONJUGATES THEREOF | ADVANCED ACCELERATOR APPLICATIONS SA (FR) | 2019-04-25 | — | — | US | disclosed |
| US-10196421-B2 | Nucleophile-reactive sulfonated compounds for the (radio)labelling of (bio)molecules; precursors and conjugates thereof | ADVANCED ACCELERATOR APPLICATIONS SA (FR) | 2019-02-05 | — | — | US | disclosed |
| EP-2399895-B1 | Process for producing optically active aliphatic fluoroalcohol | KANTO KAGAKU (JP) | 2018-08-08 | — | — | EP | disclosed |
| US-9802963-B2 | Fluorine-containing complex compound, and production method for fluorine-containing organic compound employing same | DAIKIN INDUSTRIES, LTD. (JP) | 2017-10-31 | — | — | US | disclosed |
| US-20170158731-A1 | NUCLEOPHILE-REACTIVE SULFONATED COMPOUNDS FOR THE (RADIO)LABELLING OF (BIO)MOLECULES; PRECURSORS AND CONJUGATES THEREOF | ADVANCED ACCELERATOR APPLICATIONS SA (FR) | 2017-06-08 | — | — | US | disclosed |
| US-20170158731-A1 | NUCLEOPHILE-REACTIVE SULFONATED COMPOUNDS FOR THE (RADIO)LABELLING OF (BIO)MOLECULES; PRECURSORS AND CONJUGATES THEREOF | ADVANCED ACCELERATOR APPLICATIONS SA (FR) | 2017-06-08 | — | — | US | disclosed |
| US-9611215-B2 | Nucleophile-reactive sulfonated compounds for the (radio)labelling of (bio) molecules; precursors and conjugates thereof | ADVANCED ACCELERATOR APPLICATIONS SA (FR) | 2017-04-04 | — | — | US | disclosed |
| US-9611215-B2 | Nucleophile-reactive sulfonated compounds for the (radio)labelling of (bio) molecules; precursors and conjugates thereof | ADVANCED ACCELERATOR APPLICATIONS SA (FR) | 2017-04-04 | — | — | US | disclosed |
| US-20160214999-A1 | FLUORINE-CONTAINING COMPLEX COMPOUND, AND PRODUCTION METHOD FOR FLUORINE-CONTAINING ORGANIC COMPOUND EMPLOYING SAME | DAIKIN INDUSTRIES, LTD. (JP) | 2016-07-28 | — | — | US | disclosed |
| US-20150284326-A1 | NEW NUCLEOPHILE-REACTIVE SULFONATED COMPOUNDS FOR THE (RADIO)LABELLING OF (BIO) MOLECULES; PRECURSORS AND CONJUGATES THEREOF | ADVANCED ACCELERATOR APPLICATIONS SA (FR) | 2015-10-08 | — | — | US | disclosed |
| US-20150284326-A1 | NEW NUCLEOPHILE-REACTIVE SULFONATED COMPOUNDS FOR THE (RADIO)LABELLING OF (BIO) MOLECULES; PRECURSORS AND CONJUGATES THEREOF | ADVANCED ACCELERATOR APPLICATIONS SA (FR) | 2015-10-08 | — | — | US | disclosed |
| US-9101635-B2 | Inhibitors of filovirus entry into host cells | MICROBIOTIX, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| US-8558033-B2 | Process for producing optically active aliphatic fluoroalcohol | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2013-10-15 | — | — | US | disclosed |
| US-8314141-B2 | Inhibitors of serine proteases, particularly hepatitis C virus NS3 protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-11-20 | — | — | US | disclosed |
| US-20120189614-A1 | INHIBITORS OF FILOVIRUS ENTRY INTO HOST CELLS | Crobiotix, Inc. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20110319671-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALIPHATIC FLUOROALCOHOL | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2011-12-29 | — | — | US | disclosed |
| EP-2399895-A2 | Process for producing optically active aliphatic fluoroalcohol | Kanto Kagaku Kabushiki Kaisha (JP) | 2011-12-28 | — | — | EP | disclosed |
| US-20090143312-A1 | INHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3 PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120189614-A1 | INHIBITORS OF FILOVIRUS ENTRY INTO HOST CELLS | BSG, SLCO1B3, SLCO2B1 | LMNA 1385/4885GAA 618/4885ALDH1A1 1308/4885 |
| US-20190119316-A1 | NEW NUCLEOPHILE-REACTIVE SULFONATED COMPOUNDS FOR THE (RADIO)LABELLING OF (BIO)MOLECULES; PRECURSORS AND CONJUGATES THEREOF | TST, STS, SULT1E1 | LMNA 4325/4885GAA 2455/4885ALDH1A1 541/4885 |
| US-20170158731-A1 | NUCLEOPHILE-REACTIVE SULFONATED COMPOUNDS FOR THE (RADIO)LABELLING OF (BIO)MOLECULES; PRECURSORS AND CONJUGATES THEREOF | SULT1E1, TST, SULT1A1 | LMNA 3021/4885GAA 2402/4885ALDH1A1 285/4885 |
| US-20150284326-A1 | NEW NUCLEOPHILE-REACTIVE SULFONATED COMPOUNDS FOR THE (RADIO)LABELLING OF (BIO) MOLECULES; PRECURSORS AND CONJUGATES THEREOF | SULT1E1, SULT1A1, TST | LMNA 3381/4885GAA 2400/4885ALDH1A1 211/4885 |
| US-20090143312-A1 | INHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3 PROTEASE | HPN, PRSS1, PRSS3 | LMNA 2150/4885GAA 568/4885ALDH1A1 3201/4885 |
| US-20160214999-A1 | FLUORINE-CONTAINING COMPLEX COMPOUND, AND PRODUCTION METHOD FOR FLUORINE-CONTAINING ORGANIC COMPOUND EMPLOYING SAME | AFF1, AFF2, AFF4 | LMNA 4791/4885GAA 3965/4885ALDH1A1 1452/4885 |
| US-10196421-B2 | Nucleophile-reactive sulfonated compounds for the (radio)labelling of (bio)molecules; precursors and conjugates thereof | SULT1E1, TST, SULT1A1 | LMNA 3021/4885GAA 2402/4885ALDH1A1 285/4885 |
| US-20110319671-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALIPHATIC FLUOROALCOHOL | ADH1A, ADH1C, ADH5 | LMNA 3133/4885GAA 531/4885ALDH1A1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.