Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.61 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4088532 | 1.00 | TRPV1 (0.61) | TRPV1TRPM8MAPK1OPRK1MEN1 | |
| SCHEMBL4078851 | 0.87 | TRPV1 (0.67) | TRPV1TRPM8 | |
| SCHEMBL4083683 | 0.87 | TRPV1 (0.67) | TRPV1TRPM8 | |
| SCHEMBL13892352 | 0.84 | POLB (0.55) | MAPK1OPRK1MEN1PKMKMT2A | |
| SCHEMBL4311591 | 0.81 | TRPV1 (0.76) | TRPV1TRPM8 | |
| SCHEMBL11886340 | 0.80 | TRPV1 (0.74) | TRPV1TRPM8 | |
| SCHEMBL11886519 | 0.80 | TRPV1 (0.74) | TRPV1TRPM8 | |
| SCHEMBL11886341 | 0.80 | TRPV1 (0.74) | TRPV1TRPM8 | |
| SCHEMBL4088451 | 0.80 | TRPV1 (0.74) | TRPV1TRPM8 | |
| SCHEMBL4081078 | 0.78 | TRPM8 (0.85) | TRPV1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871288-B2 | Aromatic neomenthylamides as flavoring substances | SYMRISE AG (DE) | 2014-10-28 | — | — | US | disclosed |
| US-8871288-B2 | Aromatic neomenthylamides as flavoring substances | SYMRISE AG (DE) | 2014-10-28 | — | — | US | disclosed |
| US-8871288-B2 | Aromatic neomenthylamides as flavoring substances | SYMRISE AG (DE) | 2014-10-28 | — | — | US | disclosed |
| EP-2064959-B1 | Aromatic Neomenthylamides as flavouring agents | SYMRISE AG (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-2064959-A1 | Aromatic Neomenthylamides as flavouring agents | Symrise GmbH & Co. KG (DE) | 2009-06-03 | — | — | EP | disclosed |
| US-20090110796-A1 | AROMATIC NEOMENTHYLAMIDES AS FLAVORING SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2009-04-30 | — | — | US | disclosed |
| US-20090110796-A1 | AROMATIC NEOMENTHYLAMIDES AS FLAVORING SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2009-04-30 | — | — | US | disclosed |
| US-20090110796-A1 | AROMATIC NEOMENTHYLAMIDES AS FLAVORING SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090110796-A1 | AROMATIC NEOMENTHYLAMIDES AS FLAVORING SUBSTANCES | AOC3, NPR3, AOC2 | TRPV1 716/4885TRPM8 1514/4885MAPK1 3893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.