Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 5/20 | 0.57 |
| ▸ | GABBR1 | Q9UBS5 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341475 | 0.91 | GABBR2 (0.67) | GABBR2GABBR1LMNACYP2C9CYP3A4 | |
| SCHEMBL340904 | 0.91 | GABBR2 (0.67) | GABBR2GABBR1LMNACYP2C9CYP3A4 | |
| 4-Amino-3- (5-Chlorothien-2-Yl)Butanoic Acid SCHEMBL342009 | 0.73 | GABBR2 (1.00) | GABBR2GABBR1LMNACYP2C9CYP3A4 | |
| SCHEMBL1520622 | 0.72 | ALOX5 (0.46) | GABBR2GABBR1LMNACYP2C9NFKB1 | |
| SCHEMBL4242299 | 0.72 | GABBR2 (0.41) | GABBR2GABBR1KMT2AGAADAO | |
| SCHEMBL9489532 | 0.72 | ALOX5 (0.49) | GABBR2GABBR1LMNACYP2C9CYP3A4 | |
| SCHEMBL164188 | 0.71 | ALOX5 (0.44) | GABBR2GABBR1LMNACYP2C9NFKB1 | |
| SCHEMBL10740698 | 0.69 | ALDH1A1 (0.44) | GABBR2GABBR1LMNACYP2C9NFKB1 | |
| SCHEMBL4240529 | 0.67 | DAO (0.45) | CYP2C9DRD3CYP2D6CYP2C19MEN1 | |
| SCHEMBL21273058 | 0.66 | ALOX5 (0.40) | GABBR2GABBR1LMNACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090252786-A1 | Use of a Biologically Active Blood Serum for the Treatment of a Disorder Characterized in a Reduced Function of a GABA Receptor | OWEN HOLDING LTD. (GB) | 2009-10-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090252786-A1 | Use of a Biologically Active Blood Serum for the Treatment of a Disorder Characterized in a Reduced Function of a GABA Receptor | GABBR1, GABBR2, GABRA2 | GABBR2 2/4885GABBR1 1/4885LMNA 2397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.