Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR1D | P28221 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4307557 | 0.94 | KDM4E (0.52) | KDM4EMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4310718 | 0.84 | KDM4E (0.68) | KDM4EMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL15134852 | 0.83 | RAB9A (0.71) | KDM4EMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4302850 | 0.83 | FAAH (0.47) | MAPTSMN1; SMN2POLBNPSR1TDP1 | |
| SCHEMBL2218360 | 0.83 | KDM4E (0.51) | KDM4EMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL24381873 | 0.83 | KDM4E (0.54) | KDM4EMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4312827 | 0.81 | CA12 (0.56) | ALDH1A1SMN1; SMN2DUSP3PTPN5PTPN11 | |
| SCHEMBL4301473 | 0.81 | KDM4E (0.59) | KDM4EMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5466334 | 0.81 | TAS1R3 (0.65) | KDM4EMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4303277 | 0.80 | KDM4E (0.58) | KDM4EMAPTALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118303-A1 | SEROTONIN 5-HT3 RECEPTOR AGONIST | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2009-05-07 | — | — | US | disclosed |
| US-7485646-B2 | Serotonin 5-HT3 receptor agonist | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2009-02-03 | — | — | US | disclosed |
| US-20070265277-A1 | Serotonin 5-Ht3 Receptor Agonist | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-11-15 | — | — | US | disclosed |
| EP-1798227-A1 | SEROTONIN 5-HT3 RECEPTOR AGONIST | Research Foundation Itsuu Laboratory (JP) | 2007-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118303-A1 | SEROTONIN 5-HT3 RECEPTOR AGONIST | HTR3A, HTR7, HTR1A | KDM4E 3740/4885MAPT 4268/4885ALDH1A1 2805/4885 |
| US-20070265277-A1 | Serotonin 5-Ht3 Receptor Agonist | HTR3A, HTR7, HTR1A | KDM4E 3740/4885MAPT 4268/4885ALDH1A1 2805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.