Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.38 |
| ▸ | BCHE | P06276 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4310531 | 0.75 | ALDH1A1 (0.41) | HTR2AALDH1A1MAPTHPGD | |
| SCHEMBL4304595 | 0.72 | PTGS2 (0.42) | DRD2DRD3DRD1DRD5CA12 | |
| SCHEMBL7049728 | 0.72 | PTGS2 (0.42) | ACHEBCHEHTR2ADRD2DRD3 | |
| SCHEMBL11594055 | 0.68 | DRD2 (0.44) | HTR2ADRD2DRD3DRD1DRD5 | |
| SCHEMBL28344811 | 0.67 | CYP3A4 (0.44) | MAPT | |
| SCHEMBL7056142 | 0.67 | HTR2A (0.40) | ACHEBCHEHTR2ADRD2DRD3 | |
| SCHEMBL6907003 | 0.66 | DRD2 (0.62) | ACHEHTR2ADRD2DRD3DRD1 | |
| SCHEMBL915094 | 0.66 | TRPA1 (0.40) | ACHEBCHEHTR2ADRD2DRD3 | |
| SCHEMBL2959751 | 0.66 | ACHE (0.35) | ACHEBCHEPTGS2 | |
| Ammonia Solution, Strong SCHEMBL3583671 | 0.65 | DRD2 (0.61) | HTR2ADRD2DRD3DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136965-A1 | COMPOSITIONS AND METHODS COMPRISING CAPURAMYCIN ANALOGUES | SEQUELLA, INC. (US) | 2009-11-12 | — | — | WO | disclosed |