Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.32 |
| ▸ | FNTA | P49354 | 2/20 | 0.31 |
| ▸ | FNTB | P49356 | 2/20 | 0.31 |
| ▸ | CASP3 | P42574 | 3/20 | 0.30 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.30 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777378 | 0.80 | CYP2D6 (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9638972 | 0.76 | GPR139 (0.34) | CA2CA4HDAC3HDAC4HDAC1 | |
| SCHEMBL13301145 | 0.72 | FOLH1 (0.56) | FNTAFNTB | |
| SCHEMBL10068467 | 0.72 | CASP3 (0.56) | CASP3CASP8CASP1 | |
| SCHEMBL4311125 | 0.72 | CASP3 (0.56) | CASP3CASP8CASP1 | |
| SCHEMBL9021123 | 0.70 | CA2 (0.58) | CA2CA4FNTAFNTBCASP3 | |
| SCHEMBL9020944 | 0.70 | CA2 (0.58) | CA2CA4FNTAFNTBCASP3 | |
| SCHEMBL9729998 | 0.69 | HDAC3 (0.37) | CA2CA4HDAC3HDAC4HDAC1 | |
| SCHEMBL10447493 | 0.68 | ALDH1A1 (0.41) | CA2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9730277 | 0.67 | ALDH1A1 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337853-B1 | AN EXTENDED TETHERING APPROACH FOR RAPID IDENTIFICATION OF LIGANDS | SUNESIS PHARMACEUTICALS INC (US) | 2009-01-07 | — | — | EP | disclosed |