Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 12/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31182983 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1SIRT2CHRM5CHKA | |
| Hydrochloric Acid SCHEMBL10503994 | 0.98 | SIRT2 (0.44) | KDM4EALDH1A1SIRT2CHRM5CHKA | |
| SCHEMBL9480589 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1SIRT2CHRM5CHKA | |
| SCHEMBL4311559 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1SIRT2CHRM5CHKA | |
| SCHEMBL29907776 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1SIRT2CHRM5CHKA | |
| SCHEMBL4308808 | 0.80 | ALDH1A1 (0.50) | KDM4EALDH1A1SIRT2CHRM5CHKA | |
| SCHEMBL15211555 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1SIRT2CHRM5CHKA | |
| SCHEMBL15212887 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1SIRT2CHRM5CHKA | |
| SCHEMBL7664616 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1SIRT2CHRM5CHKA | |
| SCHEMBL27474726 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1SIRT2CHRM5CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9533297-B2 | Ligands designed to provide highly active catalyst complexes | CARNEGIE MELLON UNIVERSITY (US) | 2017-01-03 | — | — | US | disclosed |
| US-20150087795-A1 | LIGANDS DESIGNED TO PROVIDE HIGHLY ACTIVE CATALYST COMPLEXES | CARNEGIE MELLON UNIVERSITY | 2015-03-26 | — | — | US | disclosed |
| WO-2013126745-A2 | LIGANDS DESIGNED TO PROVIDE HIGHLY ACTIVE CATALYST COMPLEXES | CARNEGIE MELLON UNIVERSITY (US) | 2013-08-29 | — | — | WO | disclosed |
| US-20090044345-A1 | Use of Metal Complex Compounds as Oxidation Catalysts | CIBA CORP. | 2009-02-19 | — | — | US | disclosed |
| US-20090044345-A1 | Use of Metal Complex Compounds as Oxidation Catalysts | CIBA CORP. | 2009-02-19 | — | — | US | disclosed |
| US-20090044345-A1 | Use of Metal Complex Compounds as Oxidation Catalysts | CIBA CORP. | 2009-02-19 | — | — | US | disclosed |
| EP-1981635-A1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | Ciba Holding Inc. (CH) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007090461-A1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | CIBA HOLDING INC. (CH) | 2007-08-16 | — | — | WO | disclosed |
| WO-2007090461-A1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | CIBA HOLDING INC. (CH) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090044345-A1 | Use of Metal Complex Compounds as Oxidation Catalysts | MT-CO2, MT-CO1, SOD1 | KDM4E 3219/4885ALDH1A1 984/4885SIRT2 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.