SCHEMBL430940

SCHEMBL430940

Cc1ccccc1[C](c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
HPGD P15428 4/20 0.45
KCNK3 O14649 1/20 0.44
KCNK9 Q9NPC2 1/20 0.44
ERCC5 P28715 1/20 0.44
FEN1 P39748 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
ALDH1A1 P00352 2/20 0.43
TSHR P16473 1/20 0.43
ACHE P22303 1/20 0.43
KMT2A Q03164 1/20 0.42
MYC P01106 1/20 0.41
POLB P06746 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL336772 0.95 NPC1 (0.46) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL2038760 0.84 ACHE (0.53) HPGDERCC5FEN1SMN1; SMN2ALDH1A1
SCHEMBL3461999 0.78 NPC1 (0.44) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL4711341 0.76 NPC1 (0.43) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL236 0.76 AKR1C3 (0.61) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL6445437 0.76 KMT2A (0.45) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL11757827 0.76 ALDH1A1 (0.49) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL11108075 0.76 CYP1A2 (0.49) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL9451511 0.76 AKR1C3 (0.61) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL29883083 0.76 KMT2A (0.45) NPC1RAB9AHPGDKCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 562 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110291099-B Synthesis of Liraglutide 拜康有限公司 2024-06-21 CN claimed
EP-4380962-A1 PROCESS FOR THE PREPARATION OF SEMAGLUTIDE MSN Laboratories Private Limited, R&D Center (IN) 2024-06-12 EP claimed
US-11827667-B2 Production method for guanosine derivative having fluorine atom-containing functional group at position 8 and application thereof UNIVERSITY OF MIYAZAKI (JP) 2023-11-28 US claimed
WO-2023090935-A1 METHOD FOR PRODUCING AGM PEPTIDES THAT BIND SPECIFICALLY TO NUCLEOLIN 애니젠 주식회사 2023-05-25 WO claimed
WO-2023012829-A1 PROCESS FOR THE PREPARATION OF SEMAGLUTIDE MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) 2023-02-09 WO claimed
US-11066439-B2 Synthesis of liraglutide BIOCON LIMITED (IN) 2021-07-20 US claimed
US-20200079817-A1 SYNTHESIS OF LIRAGLUTIDE BIOCON LIMITED (IN) 2020-03-12 US claimed
EP-3551643-A1 SYNTHESIS OF LIRAGLUTIDE Biocon Limited (IN) 2019-10-16 EP claimed
CN-110291099-A The synthesis of Liraglutide 拜康有限公司 2019-09-27 CN claimed
CN-109790208-A Method for preparing peptides comprising lipophilically modified lysine side chains 赛诺菲 2019-05-21 CN claimed
EP-1021388-B1 PHOSPHORYLATION PROCESS AND CATALYST BIONERIS AB (SE) 2003-06-25 EP claimed
EP-1309730-A2 NEW HYDRAZIDE BUILDING BLOCKS AND HYDRAZIDE MODIFIED BIOMOLECULES Nanogen Recognomics GmbH (DE) 2003-05-14 EP claimed
US-6528655-B1 Hydroxyphenyl diamido derivatives PHARMACOR, INC. (CA) 2003-03-04 US claimed
US-6479656-B1 Phosphorylation process and catalyst PERSTORP AB (SE) 2002-11-12 US claimed
WO-2002026697-A2 AROMATIC DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES PHARMACOR, INC. (CA) 2002-04-04 WO claimed
WO-2002014558-A2 NEW HYDRAZIDE BUILDING BLOCKS AND HYDRAZIDE MODIFIED BIOMOLECULES NANOGEN RECOGNOMICS GMBH (DE) 2002-02-21 WO claimed
EP-1179537-A1 SOLID PHASE PEPTIDE SYNTHESIS METHOD Lipotec, S.A. (ES) 2002-02-13 EP claimed
JP-2001501910-A 2001-02-13 JP claimed
EP-1021388-A1 PHOSPHORYLATION PROCESS AND CATALYST PERSTORP AB (SE) 2000-07-26 EP claimed
WO-1997034853-A1 PHOSPHORYLATION PROCESS AND CATALYST PERSTORP AB (SE) 1997-09-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11827667-B2 Production method for guanosine derivative having fluorine atom-containing functional group at position 8 and application thereof RNMT, FBL, NOP2 NPC1 2063/4885RAB9A 1390/4885HPGD 1034/4885
US-11066439-B2 Synthesis of liraglutide GLP1R, GIPR, IAPP NPC1 3897/4885RAB9A 3335/4885HPGD 4293/4885
US-20200079817-A1 SYNTHESIS OF LIRAGLUTIDE GLP1R, GIPR, IAPP NPC1 3897/4885RAB9A 3335/4885HPGD 4293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.