SCHEMBL336772

SCHEMBL336772

Cc1ccccc1[C](c1ccccc1)c1ccccc1C

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
HPGD P15428 4/20 0.45
KCNK3 O14649 1/20 0.44
KCNK9 Q9NPC2 1/20 0.44
ERCC5 P28715 1/20 0.44
FEN1 P39748 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
ALDH1A1 P00352 2/20 0.43
TSHR P16473 1/20 0.43
ACHE P22303 1/20 0.43
KMT2A Q03164 2/20 0.42
MYC P01106 1/20 0.41
POLB P06746 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL430940 0.95 NPC1 (0.46) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL2038760 0.84 ACHE (0.53) HPGDERCC5FEN1SMN1; SMN2ALDH1A1
SCHEMBL3461999 0.78 NPC1 (0.44) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL4711341 0.76 NPC1 (0.43) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL236 0.76 AKR1C3 (0.61) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL6445437 0.76 KMT2A (0.45) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL9451511 0.76 AKR1C3 (0.61) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL11757827 0.76 ALDH1A1 (0.49) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL11108075 0.76 CYP1A2 (0.49) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL29402362 0.76 AKR1C3 (0.61) NPC1RAB9AHPGDKCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 414 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084988-A Polymerization monomer for preparing beta-1, 3 glucan and polymerization method 山东大学 2024-05-28 CN claimed
US-11827667-B2 Production method for guanosine derivative having fluorine atom-containing functional group at position 8 and application thereof UNIVERSITY OF MIYAZAKI (JP) 2023-11-28 US claimed
CN-111925403-A Glucosamine donors and application thereof 山东大学 2020-11-13 CN claimed
US-8592214-B2 Chemical reaction monitor ILLUMINA, INC. (US) 2013-11-26 US claimed
US-20130052690-A1 PCR PRIMER AND METHOD FOR REDUCING NON-SPECIFIC NUCLEIC ACID AMPLIFICATION USING A PHOTOLABILE PROTECTING GROUP SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-02-28 US claimed
US-20110136684-A1 CHEMICAL REACTION MONITOR ILLUMINA, INC. 2011-06-09 US claimed
US-7887752-B2 Simultaneous data gathering for multiwell plates; light emitting diode illumination, camera image recording and computer storage and analysis; such as following dimethoxytrityl deprotection step during DNA chain synthesis to determine coupling efficiency ILLUMINA, INC. (US) 2011-02-15 US claimed
US-7718579-B2 Electrochemical deblocking using a hydrazine derivative COMBIMATRIX CORPORATION (US) 2010-05-18 US claimed
EP-2045004-A1 Method of manufacturing polymer array by coating photosensitizer Samsung Electronics Co., Ltd. (KR) 2009-04-08 EP claimed
EP-1805206-A2 ELECTROCHEMICAL DEBLOCKING USING A HYDRAZINE DERIVATIVE Combimatrix Corporation (US) 2007-07-11 EP claimed
WO-2006031814-A2 ELECTROCHEMICAL DEBLOCKING USING A HYDRAZINE DERIVATIVE COMBIMATRIX CORPORATION (US) 2006-03-23 WO claimed
US-20060054511-A1 Electrochemical deblocking using a hydrazine derivative CUSTOMARRAY, INC. 2006-03-16 US claimed
WO-2006019471-A2 FLUID PROCESSING DEVICE APPLERA CORPORATION (US) 2006-02-23 WO claimed
US-20060013742-A1 Fluid processing device APPLIED BIOSYSTEMS, LLC 2006-01-19 US claimed
EP-1236736-A1 2-AMINOPURINE DERIVATIVES HISAMITSU PHARMACEUTICAL CO. INC. (JP) 2002-09-04 EP claimed
US-5221736-A Sequential peptide and oligonucleotide syntheses using immunoaffinity techniques BIONEBRASKA, INC. (US) 1993-06-22 US claimed
JP-60215685-A None JP disclosed
WO-2024151257-A1 NUCLEOTIDE EXTENSION CHAIN VERIFICATION AGILENT TECHNOLOGIES, INC. (US) 2024-07-18 WO disclosed
WO-1990006045-A2 NUCLEIC ACID PROBES DYNAL AS (NO) 1990-06-14 WO disclosed
JP-S60215685-A 2'-DEOXYARISTEROMYCIN DERIVATIVE AND ITS USE TAKEDA CHEM IND LTD 1985-10-29 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130052690-A1 PCR PRIMER AND METHOD FOR REDUCING NON-SPECIFIC NUCLEIC ACID AMPLIFICATION USING A PHOTOLABILE PROTECTING GROUP POLL, POLRMT, POLN NPC1 3926/4885RAB9A 3856/4885HPGD 2897/4885
US-11827667-B2 Production method for guanosine derivative having fluorine atom-containing functional group at position 8 and application thereof RNMT, FBL, NOP2 NPC1 2063/4885RAB9A 1390/4885HPGD 1034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.