Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28431544 | 0.85 | MAPT (0.47) | CYP2A6MAPTAPPSNCAHPGD | |
| SCHEMBL17936545 | 0.84 | CYP2A6 (0.41) | CYP2A6MAPTAPPSNCAHPGD | |
| SCHEMBL15428925 | 0.84 | CYP2A6 (0.41) | CYP2A6MAPTAPPSNCAHPGD | |
| SCHEMBL4322658 | 0.83 | MAPT (0.49) | MAPTHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28758819 | 0.82 | UTS2R (0.46) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL16682553 | 0.81 | MAPT (0.39) | CYP2A6MAPTAPPSNCAHPGD | |
| SCHEMBL4976553 | 0.81 | MAPT (0.49) | CYP2A6MAPTAPPSNCAHPGD | |
| SCHEMBL34895 | 0.80 | MAPT (0.53) | CYP2A6MAPTAPPHPGDALDH1A1 | |
| SCHEMBL30898565 | 0.80 | MAPT (0.53) | CYP2A6MAPTAPPHPGDALDH1A1 | |
| SCHEMBL1177340 | 0.79 | CYP2A6 (0.47) | CYP2A6MAPTHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130236922-A1 | COPPER(I)-ION SELECTIVE FLUORESCENT PROBE, METHOD FOR PREPARING THE SAME, METHOD FOR DIAGNOSING MALIGNANT DISEASE AND DIAGNOSIS KIT USING THE PROBE | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2013-09-12 | — | — | US | claimed |
| WO-2016114722-A1 | ALPHA-CELL SELECTIVE PROBE FOR EX-VIVO TWO PHOTON IMAGING OF ALPHA CELLS IN INTACT PANCREATIC ISLETS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-07-21 | — | — | WO | disclosed |
| US-20160022642-A1 | Compounds Useful for Promoting Protein Degradation and Methods Using Same | YALE UNIVERSITY | 2016-01-28 | — | — | US | disclosed |
| US-20160022642-A1 | Compounds Useful for Promoting Protein Degradation and Methods Using Same | YALE UNIVERSITY | 2016-01-28 | — | — | US | disclosed |
| US-20160022642-A1 | Compounds Useful for Promoting Protein Degradation and Methods Using Same | YALE UNIVERSITY | 2016-01-28 | — | — | US | disclosed |
| US-20150119435-A1 | COMPOUNDS USEFUL FOR PROMOTING PROTEIN DEGRADATION AND METHODS USING SAME | YALE UNIVERSITY | 2015-04-30 | — | — | US | disclosed |
| US-20150119435-A1 | COMPOUNDS USEFUL FOR PROMOTING PROTEIN DEGRADATION AND METHODS USING SAME | YALE UNIVERSITY | 2015-04-30 | — | — | US | disclosed |
| US-20150119435-A1 | COMPOUNDS USEFUL FOR PROMOTING PROTEIN DEGRADATION AND METHODS USING SAME | YALE UNIVERSITY | 2015-04-30 | — | — | US | disclosed |
| EP-2846784-A1 | COMPOUNDS USEFUL FOR PROMOTING PROTEIN DEGRADATION AND METHODS USING SAME | Yale University (US) | 2015-03-18 | — | — | EP | disclosed |
| EP-2075245-B1 | Two-photon probe for real-time monitoring of intracellular calcium ions, method for preparing the probe and method for real-time monitoring of intracellular calcium ions using the probe | UNIV KOREA IND & ACAD COOP (KR) | 2014-12-31 | — | — | EP | disclosed |
| US-20090286275-A1 | Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe | SFC CO., LTD. (KR) | 2009-11-19 | — | — | US | disclosed |
| EP-2075245-A2 | Two-photon probe for real-time monitoring of intracellular calcium ions, method for preparing the probe and method for real-time monitoring of intracellular calcium ions using the probe | Korea University Industry and Academy Cooperation Foundation (KR) | 2009-07-01 | — | — | EP | disclosed |
| EP-2075245-A2 | Two-photon probe for real-time monitoring of intracellular calcium ions, method for preparing the probe and method for real-time monitoring of intracellular calcium ions using the probe | Korea University Industry and Academy Cooperation Foundation (KR) | 2009-07-01 | — | — | EP | disclosed |
| US-20090155837-A1 | Two-photon fluorescent probes for acidic vesicles in live cells and tissue and method of imaging acidic vesicles in live cells and tissue using the same | SFC CO., LTD. (KR) | 2009-06-18 | — | — | US | disclosed |
| US-7511167-B2 | Two-photon dyes for real-time imaging of lipid rafts | Korea University Industry and Academy Cooperation Foundation (KR) | 2009-03-31 | — | — | US | disclosed |
| US-7511167-B2 | Two-photon dyes for real-time imaging of lipid rafts | Korea University Industry and Academy Cooperation Foundation (KR) | 2009-03-31 | — | — | US | disclosed |
| US-20080293088-A1 | Two-photon probe for real-time monitoring of intracellular magnesium ions, method for preparing the two-photon probe and method for real-time monitoring of intracellular magnesium ions using the two-photon probe | SFC CO., LTD. (KR) | 2008-11-27 | — | — | US | disclosed |
| US-20080293088-A1 | Two-photon probe for real-time monitoring of intracellular magnesium ions, method for preparing the two-photon probe and method for real-time monitoring of intracellular magnesium ions using the two-photon probe | SFC CO., LTD. (KR) | 2008-11-27 | — | — | US | disclosed |
| US-20080071106-A1 | Two-photon dyes for real-time imaging of lipid rafts | Korea University Industry and Academy Cooperation Foundation (KR) | 2008-03-20 | — | — | US | disclosed |
| US-20080071106-A1 | Two-photon dyes for real-time imaging of lipid rafts | Korea University Industry and Academy Cooperation Foundation (KR) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119435-A1 | COMPOUNDS USEFUL FOR PROMOTING PROTEIN DEGRADATION AND METHODS USING SAME | PSMG3, ERAP1, SMURF2 | CYP2A6 3077/4885MAPT 2291/4885APP 188/4885 |
| US-20090286275-A1 | Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe | SLC39A3, SLC30A7, SLC39A7 | CYP2A6 1869/4885MAPT 3270/4885APP 939/4885 |
| US-20090155837-A1 | Two-photon fluorescent probes for acidic vesicles in live cells and tissue and method of imaging acidic vesicles in live cells and tissue using the same | LAMP2, ANXA2, CHMP4B | CYP2A6 4749/4885MAPT 1989/4885APP 2554/4885 |
| US-20160022642-A1 | Compounds Useful for Promoting Protein Degradation and Methods Using Same | AR, SHBG, PSMG3 | CYP2A6 1329/4885MAPT 2379/4885APP 334/4885 |
| US-20080293088-A1 | Two-photon probe for real-time monitoring of intracellular magnesium ions, method for preparing the two-photon probe and method for real-time monitoring of intracellular magnesium ions using the two-photon probe | HRH3, CA2, HRH2 | CYP2A6 2136/4885MAPT 3833/4885APP 2722/4885 |
| US-20130236922-A1 | COPPER(I)-ION SELECTIVE FLUORESCENT PROBE, METHOD FOR PREPARING THE SAME, METHOD FOR DIAGNOSING MALIGNANT DISEASE AND DIAGNOSIS KIT USING THE PROBE | SLC30A6, SLC30A7, SLC39A7 | CYP2A6 3130/4885MAPT 3163/4885APP 2167/4885 |
| US-20080071106-A1 | Two-photon dyes for real-time imaging of lipid rafts | LAMP2, FLOT1, NPC1L1 | CYP2A6 3781/4885MAPT 2674/4885APP 1772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.