Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3763384 | 0.86 | NPC1 (0.50) | MAPTRAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL10906215 | 0.86 | ALDH1A1 (0.57) | MAPTRAB9ANPC1KMT2ALMNA | |
| SCHEMBL43095 | 0.83 | CYP2A6 (0.44) | MAPTRAB9ANPC1KDM4EMAPK1 | |
| SCHEMBL18360379 | 0.82 | MAPT (0.53) | MAPTRAB9ANPC1KDM4EMAPK1 | |
| SCHEMBL8372731 | 0.80 | TSHR (0.53) | MAPTRAB9ANPC1KDM4EMAPK1 | |
| SCHEMBL2558482 | 0.80 | MAPT (0.45) | MAPTRAB9ANPC1KDM4EMAPK1 | |
| SCHEMBL8350993 | 0.80 | MAPT (0.54) | MAPTRAB9ANPC1KDM4EMAPK1 | |
| SCHEMBL797850 | 0.80 | CA2 (0.43) | GAAL3MBTL1ALDH1A1 | |
| SCHEMBL3348892 | 0.80 | KEAP1 (0.54) | RAB9AKMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL196635 | 0.79 | KMT2A (0.49) | RAB9ANPC1KDM4EKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014652-B1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | NIPPON CHEMIPHAR CO (JP) | 2014-08-06 | — | — | EP | disclosed |
| US-20130217734-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO., LTD. (JP) | 2013-08-22 | — | — | US | disclosed |
| US-8404726-B2 | Activating agent for peroxisome proliferator activated receptor δ | NIPPON CHEMIPHAR CO. LTD. (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20090298896-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO. LTD | 2009-12-03 | — | — | US | disclosed |
| EP-2014652-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298896-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | PPARA, PPARG, PPARD | MAPT 4812/4885RAB9A 2594/4885NPC1 2741/4885 |
| US-20130217734-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | PPARA, PPARG, PPARD | MAPT 4812/4885RAB9A 2594/4885NPC1 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.