Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541865 | 0.79 | CYP11B2 (0.41) | TRPA1CYP11B1CYP11B2PTGS2HTR2A | |
| SCHEMBL1923169 | 0.74 | TRPA1 (0.38) | TRPA1CYP11B1CYP11B2PTGS2PARP1 | |
| SCHEMBL1681314 | 0.72 | TRPA1 (0.36) | TRPA1CYP11B1CYP11B2PTGS2HTR2A | |
| SCHEMBL3469802 | 0.68 | TRPA1 (0.36) | TRPA1CYP11B1CYP11B2PTGS2PARP1 | |
| SCHEMBL4309791 | 0.68 | TRPA1 (0.36) | TRPA1CYP11B1CYP11B2PTGS2PARP1 | |
| SCHEMBL4313253 | 0.68 | TRPA1 (0.36) | TRPA1CYP11B1CYP11B2PTGS2PARP1 | |
| SCHEMBL4304595 | 0.68 | PTGS2 (0.42) | TRPA1PTGS2PARP1MAOAMAOB | |
| SCHEMBL6239530 | 0.68 | ACHE (0.39) | TRPA1PTGS2HTR2APARP1MAOA | |
| SCHEMBL8021475 | 0.68 | TRPA1 (0.37) | TRPA1CYP11B1CYP11B2PTGS2PARP1 | |
| SCHEMBL6259860 | 0.67 | CYP1A2 (0.36) | HTR2AHRH1HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1916244-A1 | THIOPHENE COMPOUND HAVING SULFONYL GROUP AND PROCESS FOR PRODUCING THE SAME | Nissan Chemical Industries, Ltd. (JP) | 2008-04-30 | — | — | EP | disclosed |