Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | USP8 | P40818 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ENPP3 | O14638 | 6/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 5/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334954 | 0.90 | MAPT (0.52) | KDM1AKCNQ1KDM4ERAB9AENPP3 | |
| SCHEMBL4330190 | 0.87 | KCNQ1 (0.53) | GSTO1KDM1AKCNQ1KDM4ERAB9A | |
| SCHEMBL4324085 | 0.87 | PHGDH (0.50) | KDM1AKDM4ERAB9AUSP2MEN1 | |
| SCHEMBL3599413 | 0.85 | GSTO1 (0.63) | GSTO1KDM1AKDM4EALOX5CSNK2A2 | |
| SCHEMBL4322753 | 0.80 | ATP4A (0.55) | KDM1ARAB9AMAPT | |
| SCHEMBL4338181 | 0.79 | MEN1 (0.48) | KDM1ARAB9AENPP1CSNK2A1MEN1 | |
| SCHEMBL3608913 | 0.73 | CCR4 (0.55) | GSTO1KDM4ERAB9AUSP2ALOX5 | |
| SCHEMBL3595657 | 0.73 | PTGS2 (0.66) | GSTO1RAB9AALOX5CSNK2A1MEN1 | |
| SCHEMBL4324290 | 0.72 | HSPA5 (0.52) | GSTO1KDM4ERAB9ACSNK2A2CSNK2B | |
| SCHEMBL3791737 | 0.72 | GSTO1 (0.72) | GSTO1KDM1AKDM4EUSP2USP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | claimed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |