Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 5/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 4/20 | 0.44 |
| ▸ | CCR4 | P51679 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4322757 | 0.90 | GSTO1 (0.51) | MAPTKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL4330190 | 0.89 | KCNQ1 (0.53) | MAPTKDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL4338181 | 0.89 | MEN1 (0.48) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL4324085 | 0.87 | PHGDH (0.50) | MAPTKDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL3608913 | 0.85 | CCR4 (0.55) | MAPTKDM4ERAB9AALDH1A1KMT2A | |
| SCHEMBL4330728 | 0.81 | ADORA3 (0.48) | MAPTKDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL4334951 | 0.80 | ATP4A (0.58) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL4324290 | 0.76 | HSPA5 (0.52) | MAPTKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL3595657 | 0.75 | PTGS2 (0.66) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL3601789 | 0.74 | KDM4E (0.60) | MAPTKDM4ERAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | claimed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |