SCHEMBL4324488

SCHEMBL4324488

C[C@H]1NCC[C@@]1(O)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 4/20 0.33
ARG2 P78540 1/20 0.33
MAPT P10636 1/20 0.32
FFAR3 O14843 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17578911 1.00 ARG1 (0.33) ARG1ARG2MAPTFFAR3
SCHEMBL4760665 1.00 ARG1 (0.33) ARG1ARG2MAPTFFAR3
SCHEMBL202804 1.00 ARG1 (0.33) ARG1ARG2MAPTFFAR3
SCHEMBL9909459 0.69
SCHEMBL28044404 0.67
SCHEMBL1644060 0.67
SCHEMBL7573288 0.66
SCHEMBL5162261 0.65
SCHEMBL27147965 0.64
SCHEMBL27096265 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420151-B2 Mixtures having a salty taste SYMRISE AG (DE) 2013-04-16 US claimed
EP-1937089-B1 MIXTURES HAVING A SALTY TASTE SYMRISE AG (DE) 2012-08-22 EP claimed
US-20090214728-A1 MIXTURES HAVING A SALTY TASTE SYMRISE GMBH & CO. KG (DE) 2009-08-27 US claimed
EP-1937089-A1 MIXTURES HAVING A SALTY TASTE Symrise GmbH & Co. KG (DE) 2008-07-02 EP claimed
WO-2007045566-A1 MIXTURES HAVING A SALTY TASTE SYMRISE GMBH & CO. KG (DE) 2007-04-26 WO claimed
US-20240114942-A1 Antagonists of T2R54 and Compositions and Uses Thereof FIRMENICH INCORPORATED (US) 2024-04-11 US disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
US-11871772-B2 Antagonists of T2R54 and compositions and uses thereof FIRMENICH INCORPORATED (US) 2024-01-16 US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
US-11553729-B1 Non-chemical named, saltiness enhancing mixture for use in ketchup and other foods, designed for marketing HANTMAN KEN (US) 2023-01-17 US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION SENOMYX INC (US) 2017-03-30 US disclosed
US-20160374367-A1 SPICE BLEND SALT SUBSTITUTE FOR KETCHUP AND TOMATO BASED FOODS, DESIGNED FOR MARKETING HANTMAN KEN (US) 2016-12-29 US disclosed
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF SENOMYX INC (US) 2016-12-29 US disclosed
US-8420151-B2 Mixtures having a salty taste SYMRISE AG (DE) 2013-04-16 US disclosed
EP-1937089-B1 MIXTURES HAVING A SALTY TASTE SYMRISE AG (DE) 2012-08-22 EP disclosed
US-20090214728-A1 MIXTURES HAVING A SALTY TASTE SYMRISE GMBH & CO. KG (DE) 2009-08-27 US disclosed
EP-1937089-A1 MIXTURES HAVING A SALTY TASTE Symrise GmbH & Co. KG (DE) 2008-07-02 EP disclosed
WO-2007045566-A1 MIXTURES HAVING A SALTY TASTE SYMRISE GMBH & CO. KG (DE) 2007-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 ARG1 1079/4885ARG2 1092/4885MAPT 4340/4885
US-11871772-B2 Antagonists of T2R54 and compositions and uses thereof TAS2R50, TAS2R30, TAS2R60 ARG1 2354/4885ARG2 1961/4885MAPT 3986/4885
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF TAS2R5, TAS1R1, TAS2R1 ARG1 1462/4885ARG2 3539/4885MAPT 930/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 ARG1 1079/4885ARG2 1092/4885MAPT 4340/4885
US-20240114942-A1 Antagonists of T2R54 and Compositions and Uses Thereof TAS2R50, TAS2R30, TAS2R60 ARG1 2354/4885ARG2 1961/4885MAPT 3986/4885
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION TRPA1, PDE6G, PDE6D ARG1 1984/4885ARG2 3173/4885MAPT 286/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 ARG1 1079/4885ARG2 1092/4885MAPT 4340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.