SCHEMBL4325302

SCHEMBL4325302

CCOC(=O)C(CCC(C)c1ccc(Br)cc1)c1nccs1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 4/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
CTSA P10619 6/20 0.36
PKM P14618 2/20 0.36
ALDH1A1 P00352 1/20 0.36
FFAR2 O15552 2/20 0.35
IDO1 P14902 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4322239 0.86 CTSA (0.37) MEN1KMT2ACTSAALDH1A1FFAR2
SCHEMBL4320613 0.84 FFAR2 (0.38) MEN1KMT2AFFAR2NPC1RAB9A
SCHEMBL11162453 0.81 PKM (0.41) FPR2MEN1KMT2ACTSAPKM
SCHEMBL4320658 0.77 MEN1 (0.40) FPR2MEN1KMT2ATDP1CTSA
SCHEMBL908619 0.72 ALDH1A1 (0.49) MEN1KMT2ACTSAPKMALDH1A1
SCHEMBL8429804 0.71 ALDH1A1 (0.51) MEN1KMT2ACTSAPKMALDH1A1
SCHEMBL4330530 0.70 CTSA (0.43) CTSAPKMCYP1A2CYP3A4CYP2D6
SCHEMBL4327564 0.70 CTSA (0.43) CTSAPKMCYP1A2CYP3A4CYP2D6
SCHEMBL8044956 0.70 MEN1 (0.41) MEN1KMT2ACTSAPKMCYP1A2
SCHEMBL4334693 0.70 CTSA (0.43) CTSAPKMCYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7521563-B2 Hydroxamic acid derivative and medicine containing the same as active ingredient SHIZUOKA COFFEIN CO., LTD. (JP) 2009-04-21 US disclosed
US-20070208065-A1 Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient SHIZUOKA COFFEIN CO., LTD. (JP) 2007-09-06 US disclosed
EP-1787986-A1 HYDROXAMIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME AS ACTIVE INGREDIENT SHIZUOKA COFFEIN CO., LTD. (JP) 2007-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208065-A1 Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient IL6, IL1A, TNF FPR2 1052/4885MEN1 3484/4885KMT2A 1615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.