Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.45 |
| ▸ | EIF4H | Q15056 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30871757 | 0.98 | LMNA (0.55) | TSHRCYP3A4NFKB1THPOHIF1A | |
| SCHEMBL11043739 | 0.87 | NCF1 (0.47) | TSHRCYP3A4NFKB1THPOHIF1A | |
| SCHEMBL5243080 | 0.81 | COMT (0.56) | TSHRCYP3A4NFKB1THPOHIF1A | |
| SCHEMBL11681357 | 0.81 | TSHR (0.54) | TSHRCYP3A4NFKB1THPOHIF1A | |
| SCHEMBL10050955 | 0.81 | PABPC1 (0.58) | TSHRCYP3A4NFKB1THPOHIF1A | |
| SCHEMBL1626273 | 0.81 | CA2 (0.56) | TSHRCYP3A4NFKB1THPOHIF1A | |
| SCHEMBL27419573 | 0.80 | TRPV4 (0.51) | TSHRCYP3A4NFKB1THPOHIF1A | |
| Iodide SCHEMBL29914016 | 0.80 | COMT (0.54) | TSHRCYP3A4NFKB1THPOHIF1A | |
| SCHEMBL22050086 | 0.80 | COMT (0.55) | TSHRCYP3A4NFKB1THPOHIF1A | |
| Water SCHEMBL21625620 | 0.80 | COMT (0.54) | TSHRCYP3A4NFKB1THPOHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102690259-B | Compound with function of diuresis, preparation method and functions thereof | TIANJIN INST PHARM RESEARCH | 2014-05-28 | — | — | CN | claimed |
| CN-102942558-B | Preparation method of benzazepine derivatives | TIANJIN INST PHARM RESEARCH | 2014-04-16 | — | — | CN | claimed |
| CN-102942558-A | Preparation method of benzazepine derivatives | TIANJIN INST PHARM RESEARCH | 2013-02-27 | — | — | CN | claimed |
| CN-102690259-A | Compound with function of diuresis, preparation method and functions thereof | TIANJIN INST PHARM RESEARCH | 2012-09-26 | — | — | CN | claimed |
| CN-121085840-A | Preparation method of medicine intermediate 2-amino-3-hydroxypyridine | 辽宁中舟得水环保科技有限公司 | 2025-12-09 | — | — | CN | disclosed |
| US-20250339388-A1 | PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF | MAXYMUNE THERAPEUTICS INC (US) | 2025-11-06 | — | — | US | disclosed |
| US-20250319046-A1 | PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF | MAXYMUNE THERAPEUTICS INC (US) | 2025-10-16 | — | — | US | disclosed |
| US-12427124-B1 | Phenylalanine-based LAT1 inhibitors and uses thereof | Maxymune Therapeutics, Inc. (US) | 2025-09-30 | — | — | US | disclosed |
| CN-119409685-B | 4- (1- (Azaacyl-3-butyl) -1H-imidazol-2-yl) anilides PKM2 agonists | 南京医科大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-119409685-A | 4- (1- (Azaacyl-3-butyl) -1H-imidazol-2-yl) anilides PKM2 agonists | 南京医科大学 | 2025-02-11 | — | — | CN | disclosed |
| US-20230303552-A1 | ARYLSULFONYL DERIVATIVES AND THEIR USE AS MUSCARINIC ACETYLCHOLINE RECEPTOR M5 INHIBITORS | VANDERBILT UNIVERSITY | 2023-09-28 | — | — | US | disclosed |
| US-20230303552-A1 | ARYLSULFONYL DERIVATIVES AND THEIR USE AS MUSCARINIC ACETYLCHOLINE RECEPTOR M5 INHIBITORS | VANDERBILT UNIVERSITY | 2023-09-28 | — | — | US | disclosed |
| WO-2005049023-A1 | GLYT1 TRANSPORTER INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-06-02 | — | — | WO | disclosed |
| WO-2005049023-A1 | GLYT1 TRANSPORTER INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-06-02 | — | — | WO | disclosed |
| EP-1455777-A1 | GLYT1 TRANSPORTER INHIBITORS AND USES THEREOF IN TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003055478-A1 | GLYT1 TRANSPORTER INHIBITORS AND USES THEREOF IN TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-07-10 | — | — | WO | disclosed |
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| EP-0471841-B1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ASAHI CHEMICAL IND (JP) | 1995-11-02 | — | — | EP | disclosed |
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250339388-A1 | PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF | SLC43A1, SLC7A1, SLC1A5 | TSHR 3378/4885CYP3A4 2646/4885NFKB1 1771/4885 |
| US-12427124-B1 | Phenylalanine-based LAT1 inhibitors and uses thereof | SLC43A1, SLC7A1, SLC1A5 | TSHR 3378/4885CYP3A4 2646/4885NFKB1 1771/4885 |
| US-20230303552-A1 | ARYLSULFONYL DERIVATIVES AND THEIR USE AS MUSCARINIC ACETYLCHOLINE RECEPTOR M5 INHIBITORS | CHRM5, CHRM1, CHRM2 | TSHR 52/4885CYP3A4 641/4885NFKB1 3307/4885 |
| US-20250319046-A1 | PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF | SLC43A1, SLC7A1, SLC1A5 | TSHR 3378/4885CYP3A4 2646/4885NFKB1 1771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.