Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 7/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433484 | 0.74 | HDAC1 (0.37) | TAS1R3TAS1R1TAS1R2CA12CA9 | |
| SCHEMBL434448 | 0.73 | HDAC2 (0.40) | TAS1R3TAS1R1TAS1R2PREPCA12 | |
| SCHEMBL435038 | 0.71 | MCHR1 (0.34) | GSK3BGSK3ACA12CA9MAPT | |
| SCHEMBL435039 | 0.71 | MCHR1 (0.34) | GSK3BGSK3ACA12CA9MAPT | |
| SCHEMBL434762 | 0.69 | SLC6A3 (0.45) | TAS1R3TAS1R1TAS1R2GSK3BGSK3A | |
| SCHEMBL5897217 | 0.65 | LMNA (0.55) | CA12CA9SLC6A3KCNH2TAAR1 | |
| SCHEMBL432002 | 0.65 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2GSK3BGSK3A | |
| SCHEMBL5897079 | 0.64 | LMNA (0.54) | CA12CA9SLC6A3KCNH2TAAR1 | |
| SCHEMBL955612 | 0.64 | HTT (0.50) | RAB9AMAPT | |
| SCHEMBL937205 | 0.64 | PROKR1 (0.63) | TAS1R3TAS1R1TAS1R2PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012366-A1 | PESTICIDAL 3-(ARYLOXY)AZACYCLOALKANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-26 | — | — | WO | disclosed |