Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SCD | O00767 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PHGDH | O43175 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331871 | 0.90 | ADORA3 (0.58) | ADORA3NPC1RAB9AMAPTCASP3 | |
| SCHEMBL4333461 | 0.89 | RAB9A (0.53) | ADORA3NPC1RAB9AMAPTPKM | |
| SCHEMBL4322683 | 0.88 | MEN1 (0.60) | ADORA3NPC1RAB9AMAPTPKM | |
| SCHEMBL4330728 | 0.86 | ADORA3 (0.48) | ADORA3NPC1RAB9AMAPTPKM | |
| SCHEMBL4324209 | 0.85 | RAB9A (0.44) | ADORA3NPC1RAB9AMAPTPKM | |
| SCHEMBL3598628 | 0.85 | MAPT (0.58) | ADORA3NPC1RAB9AMAPTSCD | |
| SCHEMBL4326708 | 0.83 | MAPT (0.53) | ADORA3NPC1RAB9AMAPTPKM | |
| SCHEMBL4342353 | 0.83 | RAB9A (0.50) | ADORA3NPC1RAB9AMAPTPKM | |
| SCHEMBL4330706 | 0.83 | SCD (0.70) | ADORA3NPC1RAB9AMAPTSCD | |
| SCHEMBL3615150 | 0.83 | MEN1 (0.55) | ADORA3NPC1RAB9AMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | claimed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |