Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | ACR | P10323 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331871 | 0.88 | ADORA3 (0.58) | ADORA3RAB9AKDM4EMAPTNPC1 | |
| SCHEMBL4329797 | 0.86 | ADORA3 (0.56) | ADORA3RAB9AMAPTNPC1PKM | |
| SCHEMBL3608913 | 0.86 | CCR4 (0.55) | RAB9AKDM4EMAPTALDH1A1NPSR1 | |
| SCHEMBL4324209 | 0.83 | RAB9A (0.44) | ADORA3RAB9AKDM4EMAPTNPC1 | |
| SCHEMBL4333577 | 0.82 | MAPT (0.53) | PRSS1ACRRAB9AKDM4EMAPT | |
| SCHEMBL4333461 | 0.82 | RAB9A (0.53) | ADORA3RAB9AKDM4EMAPTNPC1 | |
| SCHEMBL4326708 | 0.82 | MAPT (0.53) | ADORA3RAB9AMAPTNPC1PKM | |
| SCHEMBL3615150 | 0.82 | MEN1 (0.55) | ADORA3RAB9AKDM4EMAPTNPC1 | |
| SCHEMBL4322683 | 0.82 | MEN1 (0.60) | ADORA3RAB9AKDM4EMAPTNPC1 | |
| SCHEMBL3601789 | 0.81 | KDM4E (0.60) | ADORA3RAB9AKDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | claimed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |