Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4329797 | 0.89 | ADORA3 (0.56) | RAB9ANPC1CSNK2A1MAPTPKM | |
| SCHEMBL4331871 | 0.84 | ADORA3 (0.58) | RAB9ANPC1CSNK2A1MAPTGSTO1 | |
| SCHEMBL13578656 | 0.84 | MEN1 (0.59) | RAB9ANPC1CSNK2A1TDP1MAPT | |
| SCHEMBL4342353 | 0.83 | RAB9A (0.50) | RAB9ANPC1CSNK2A1MAPTPKM | |
| SCHEMBL4322683 | 0.82 | MEN1 (0.60) | RAB9ANPC1CSNK2A1MAPTGSTO1 | |
| SCHEMBL4330728 | 0.82 | ADORA3 (0.48) | RAB9ANPC1CSNK2A1TDP1MAPT | |
| SCHEMBL4328007 | 0.82 | ALDH1A1 (0.59) | RAB9ANPC1CSNK2A1TDP1MAPT | |
| SCHEMBL3608900 | 0.82 | RAB9A (0.67) | RAB9ANPC1CSNK2A1MAPTGSTO1 | |
| SCHEMBL30660072 | 0.82 | RAB9A (0.67) | RAB9ANPC1CSNK2A1MAPTGSTO1 | |
| SCHEMBL4324209 | 0.82 | RAB9A (0.44) | RAB9ANPC1CSNK2A1MAPTGSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | claimed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |