Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | ATP4A | P20648 | 2/20 | 0.49 |
| ▸ | ATP4B | P51164 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331871 | 0.91 | ADORA3 (0.58) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4329797 | 0.88 | ADORA3 (0.56) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3613302 | 0.84 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4333461 | 0.82 | RAB9A (0.53) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4330728 | 0.82 | ADORA3 (0.48) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4322678 | 0.81 | ATP4A (0.70) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3615150 | 0.81 | MEN1 (0.55) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3595657 | 0.79 | PTGS2 (0.66) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4324209 | 0.79 | RAB9A (0.44) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4326708 | 0.79 | MAPT (0.53) | MEN1KMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | claimed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |