Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 9/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452789 | 0.81 | PKM (0.50) | PKMKDM4E | |
| SCHEMBL4458758 | 0.77 | SIGMAR1 (0.40) | — | |
| SCHEMBL4462738 | 0.71 | MAOA (0.38) | PKMACHEKDM4E | |
| SCHEMBL4338581 | 0.71 | MAOA (0.38) | PKMACHEKDM4E | |
| SCHEMBL4459145 | 0.69 | PKM (0.43) | PKMKDM4E | |
| SCHEMBL4328800 | 0.69 | SLC6A4 (0.38) | PKMKDM4E | |
| SCHEMBL4333697 | 0.68 | MAOA (0.40) | PKMACHEKDM4E | |
| SCHEMBL4316512 | 0.67 | SLC6A4 (0.52) | — | |
| SCHEMBL4320735 | 0.67 | MAOA (0.39) | PKMKDM4E | |
| SCHEMBL31134797 | 0.66 | ABCB1 (0.55) | ACHEABCB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |