Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4340661 | 0.93 | CYP2A6 (0.42) | CYP2A6CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4329428 | 0.89 | CYP2A6 (0.43) | CYP2A6CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4334594 | 0.89 | MAPT (0.46) | CYP2A6CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4338798 | 0.88 | CYP2A6 (0.48) | CYP2A6CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4328924 | 0.88 | SLC9A1 (0.42) | CYP2A6CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4343237 | 0.86 | SIGMAR1 (0.51) | CYP2A6CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4333822 | 0.85 | ALDH1A1 (0.50) | CYP2A6CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4329107 | 0.84 | ALDH1A1 (0.45) | CYP2A6CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4324316 | 0.82 | MAPT (0.38) | CYP3A4MAPTALDH1A1POLBHPGD | |
| SCHEMBL4557720 | 0.81 | CYP2A6 (0.38) | CYP2A6CYP3A4MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090285849-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285849-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | MAVS, IRF3, HAVCR2 | CYP2A6 1906/4885CYP3A4 1045/4885MAPT 3619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.