SCHEMBL4332814

SCHEMBL4332814

CC(C)(C)Oc1ccccc1COC(=O)OCc1ccccc1OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.38
CYP4A11 Q02928 1/20 0.38
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C19 P33261 2/20 0.38
RECQL P46063 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MAPT P10636 2/20 0.38
RAB9A P51151 2/20 0.38
CACNA1B Q00975 1/20 0.37
TACR1 P25103 1/20 0.37
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37
IDO1 P14902 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ITGA4 P13612 1/20 0.36
ITGB7 P26010 1/20 0.36
HTT P42858 2/20 0.36
TP53 P04637 1/20 0.36
KMT2A Q03164 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28220575 0.88 ALDH1A1 (0.49) CYP1A2CYP3A4CYP2C19RECQLSMN1; SMN2
SCHEMBL4334989 0.88 L3MBTL1 (0.40) CYP3A4MAPTNPSR1ITGA4ITGB7
SCHEMBL18558023 0.82 IDO1 (0.41) MAPTIDO1NPSR1HTTALDH1A1
SCHEMBL286684 0.80 IDO1 (0.58) CYP1A2CYP3A4CYP2C19RECQLSMN1; SMN2
SCHEMBL18355261 0.78 IDO1 (0.46) MAPTIDO1ALDH1A1POLB
SCHEMBL12056288 0.77 L3MBTL1 (0.50) MAPTNPSR1L3MBTL1KDM4E
SCHEMBL3476430 0.77 L3MBTL1 (0.56) CYP4F2CYP4A11RECQLMAPTNPSR1
Bicarbonate SCHEMBL5277147 0.77 IDO1 (0.55) CYP1A2CYP3A4CYP2C19RECQLSMN1; SMN2
SCHEMBL5319243 0.77 L3MBTL1 (0.58) CYP3A4SMN1; SMN2MAPTMTNR1AMTNR1B
SCHEMBL8080533 0.77 CXCL8 (0.58) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3247734-B1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-08-31 EP disclosed
US-10370491-B2 Preparation of highly heat-resistant (co)polycarbonates by the transesterification method COVESTRO DEUTSCHLAND AG (DE) 2019-08-06 US disclosed
US-20170369642-A1 Preparation of Highly Heat-Resistant (Co)Polycarbonates by the Transesterification Method COVESTRO DEUTSCHLAND AG (DE) 2017-12-28 US disclosed
EP-3247734-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD Covestro Deutschland AG (DE) 2017-11-29 EP disclosed
WO-2016116480-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO DEUTSCHLAND AG (DE) 2016-07-28 WO disclosed
US-20090117314-A1 PROCESS FOR THE PREPARATION OF POLYCARBONATE BY THE MELT TRANSESTERIFICATION METHOD BAYER MATERIALSCIENCE AG (DE) 2009-05-07 US disclosed