SCHEMBL4334989

SCHEMBL4334989

CC(C)(C)Oc1ccccc1COC(=O)Oc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.40
ATM Q13315 1/20 0.40
RIPK1 Q13546 1/20 0.39
NPSR1 Q6W5P4 2/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HTT P42858 2/20 0.36
GFER P55789 1/20 0.36
HSD17B10 Q99714 1/20 0.36
FFAR1 O14842 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
ELANE P08246 2/20 0.36
ITGA4 P13612 1/20 0.35
ITGB7 P26010 1/20 0.35
TP53 P04637 1/20 0.35
PPARG P37231 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.34
HTR2A P28223 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4332814 0.88 CYP4F2 (0.38) L3MBTL1NPSR1MEN1KMT2AHTT
SCHEMBL6150724 0.82 FFAR1 (0.51) L3MBTL1RIPK1MEN1KMT2AFFAR1
SCHEMBL4343859 0.81 L3MBTL1 (0.47) L3MBTL1ATMNPSR1MEN1KMT2A
SCHEMBL28220575 0.80 ALDH1A1 (0.49) L3MBTL1HTTHSD17B10ITGA4ITGB7
SCHEMBL4342986 0.80 FFAR4 (0.46) MEN1KMT2AFFAR4ELANETP53
SCHEMBL4342476 0.79 BCHE (0.42) L3MBTL1ATMNPSR1MEN1KMT2A
SCHEMBL6151614 0.78 HTR1A (0.51) L3MBTL1MEN1KMT2AHTTGFER
SCHEMBL4332062 0.78 PPARD (0.46) L3MBTL1ATMMEN1KMT2AELANE
SCHEMBL4335280 0.78 FOS (0.45) ELANE
SCHEMBL3165775 0.78 USP2 (0.38) L3MBTL1ATMRIPK1NPSR1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3247734-B1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-08-31 EP disclosed
US-10370491-B2 Preparation of highly heat-resistant (co)polycarbonates by the transesterification method COVESTRO DEUTSCHLAND AG (DE) 2019-08-06 US disclosed
US-20170369642-A1 Preparation of Highly Heat-Resistant (Co)Polycarbonates by the Transesterification Method COVESTRO DEUTSCHLAND AG (DE) 2017-12-28 US disclosed
EP-3247734-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD Covestro Deutschland AG (DE) 2017-11-29 EP disclosed
WO-2016116480-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO DEUTSCHLAND AG (DE) 2016-07-28 WO disclosed
US-20090117314-A1 PROCESS FOR THE PREPARATION OF POLYCARBONATE BY THE MELT TRANSESTERIFICATION METHOD BAYER MATERIALSCIENCE AG (DE) 2009-05-07 US disclosed