SCHEMBL433479

SCHEMBL433479

NOC(=O)C(=Cc1ccccc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
HTT P42858 1/20 0.51
AKR1C3 P42330 1/20 0.47
AKR1C1 Q04828 1/20 0.46
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
MCL1 Q07820 1/20 0.41
NR1H4 Q96RI1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7607207 0.82 TP53 (0.55) TP53MEN1KMT2AHTTAKR1C3
SCHEMBL29898330 0.81 TP53 (0.75) TP53MEN1KMT2AHTTAKR1C3
SCHEMBL4972255 0.81 TP53 (0.68) TP53MEN1KMT2AHTTAKR1C3
SCHEMBL39098 0.81 TP53 (0.75) TP53MEN1KMT2AHTTAKR1C3
SCHEMBL4972259 0.81 TP53 (0.68) TP53MEN1KMT2AHTTAKR1C3
SCHEMBL6005632 0.81 MEN1 (0.58) TP53MEN1KMT2AHTTAKR1C3
SCHEMBL11501360 0.81 TP53 (0.53) TP53MEN1KMT2AHTTAKR1C3
SCHEMBL9333655 0.81 HTT (0.56) TP53MEN1KMT2AHTTAKR1C3
SCHEMBL3430755 0.81 MEN1 (0.58) TP53MEN1KMT2AHTTAKR1C3
SCHEMBL8207397 0.81 TP53 (0.53) TP53MEN1KMT2AHTTAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102933195-B Composition comprising a dibenzoylmethane screening agent and a merocyanine dicyano or cyanoacetate derivative, method for photostabilization of dibenzoylmethane screening agent OREAL 2015-04-01 CN claimed
EP-1484051-B1 Use of at least one blue-light screening agent to preserve the amount of endogenous carotenoids in the skin, new blue- light screening agents, cosmetic compositions. OREAL (FR) 2013-08-21 EP claimed
CN-102933195-A Composition comprising a dibenzoylmethane screening agent and a merocyanine dicyano or cyanoacetate derivative, method for photostabilization of dibenzoylmethane screening agent OREAL 2013-02-13 CN claimed
CN-102883704-A Composition comprising a dibenzoylmethane screening agent and a hydrophilic or water-soluble merocyanine uv screening agent, method for photostabilizing said dibenzoylmethane screening agent OREAL 2013-01-16 CN claimed
WO-2012010554-A1 USE OF COMPOUNDS RESULTING FROM A SUGAR POLYOL OR FROM A DEHYDROGENATED SUGAR POLYOL DERIVATIVE AS A UV-SCREENING AGENT; ANTISUN COMPOSITIONS CONTAINING SAME; AND NOVEL COMPOUNDS L'OREAL (FR) 2012-01-26 WO claimed
US-7534421-B2 s-Triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof L'OREAL (FR) 2009-05-19 US claimed
US-20090074820-A1 AMINOARYLVINYL-S-TRIAZINE COMPOUNDS AND USES THEREOF L'OREAL (FR) 2009-03-19 US claimed
US-20050008588-A1 Aminoarylvinyl-s-triazine compounds and uses thereof L'OREAL (FR) 2005-01-13 US claimed
US-20040258636-A1 Novel s-triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof SOCIETE L'OREAL S.A. (FR) 2004-12-23 US claimed
EP-1466908-A1 S-tiazin-derivatives having at least one grafted para-aminobenzalmalonic acid salt and sun screening preparations comprising those derivatives L'OREAL (FR) 2004-10-13 EP claimed
CN-114760982-B Composition comprising a cationic polysaccharide and an anionic antioxidant 莱雅公司 2024-05-31 CN disclosed
WO-2024110352-A1 HYDRATING COMPLEX AND USE IN MOISTURISING COMPOSITIONS LABORATOIRES DE BIOLOGIE VEGETALE YVES ROCHER (FR) 2024-05-30 WO disclosed
WO-2023277194-A1 SUNSCREEN W/O EMULSION L'OREAL (FR) 2023-01-05 WO disclosed
WO-2022234092-A1 Oil-in-water emulsion comprising a particular mixture of surfactants and the combination of at least one starch grafted with an acrylic polymer and of at least one starch not grafted with an acrylic polymer L'OREAL (FR) 2022-11-10 WO disclosed
EP-4076340-A1 SUN CARE COMPOSITION L'OREAL (FR) 2022-10-26 EP disclosed
US-6517742-B1 2-(butyl 4'-ylaminobenzoate)-4,6-bis((1,3,3,3-tetramethyl-1 -((trimethylsilyl)oxy)disiloxanyl)propyl-3-ylamino)-s-triazine; s-triazine derivatives substituted by at least one silicone group; from cyanuric chloride L'OREAL (FR) 2003-02-11 US disclosed
CN-1355686-A Micropigment mixture CIBA SC HOLDING AG (CH) 2002-06-26 CN disclosed
EP-0841341-B1 Sunscreen agents, and cosmetic compositions containing them OREAL (FR) 1999-04-07 EP disclosed
EP-0841341-A1 Sunscreen agents, and cosmetic compositions containing them L'OREAL (FR) 1998-05-13 EP disclosed
EP-0841341-A1 Sunscreen agents, and cosmetic compositions containing them L'OREAL (FR) 1998-05-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050008588-A1 Aminoarylvinyl-s-triazine compounds and uses thereof TYR, AAAS, ALAD TP53 1686/4885MEN1 3700/4885KMT2A 1215/4885
US-20040258636-A1 Novel s-triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof TYR, KRT18, TST TP53 143/4885MEN1 4041/4885KMT2A 495/4885
US-20090074820-A1 AMINOARYLVINYL-S-TRIAZINE COMPOUNDS AND USES THEREOF TYR, AAAS, ALAD TP53 1661/4885MEN1 3854/4885KMT2A 1027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.