SCHEMBL433480

SCHEMBL433480

NC(=C(C(=O)O)C(=O)O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.56
TDP1 Q9NUW8 3/20 0.56
TSHR P16473 2/20 0.56
CYP2C19 P33261 2/20 0.56
CYP3A4 P08684 2/20 0.56
BLM P54132 2/20 0.56
POLB P06746 1/20 0.56
PARP1 P09874 1/20 0.56
RECQL P46063 1/20 0.56
PMP22 Q01453 1/20 0.56
HSD17B10 Q99714 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
CES1 P23141 4/20 0.48
CES2 O00748 3/20 0.48
ALDH1A1 P00352 3/20 0.48
DAO P14920 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
GAA P10253 2/20 0.45
CA2 P00918 3/20 0.44
F2 P00734 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16796028 0.89 CYP2C19 (0.46) MAPTTDP1TSHRCYP2C19CYP3A4
SCHEMBL6206992 0.82 CES1 (0.55) MAPTTDP1TSHRCYP2C19CYP3A4
SCHEMBL4744290 0.81 CES2 (0.56) MAPTTDP1TSHRCYP2C19CYP3A4
SCHEMBL7778540 0.80 MAPT (0.56) MAPTTDP1TSHRCYP2C19CYP3A4
SCHEMBL6206587 0.79 CES2 (0.58) MAPTTDP1TSHRCYP2C19CYP3A4
SCHEMBL1282296 0.78 BLM (0.58) MAPTTDP1TSHRCYP2C19CYP3A4
SCHEMBL38341 0.78 BLM (0.58) MAPTTDP1TSHRCYP2C19CYP3A4
SCHEMBL1766180 0.78 BLM (0.58) MAPTTDP1TSHRCYP2C19CYP3A4
SCHEMBL6552205 0.78 MAPT (0.53) MAPTTDP1TSHRCYP3A4POLB
SCHEMBL5448660 0.78 PARP1 (0.63) MAPTPARP1L3MBTL1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117580562-A W/O type composition comprising organic UV filter and spherical hydrophobic silica 莱雅公司 2024-02-20 CN claimed
EP-1484051-B1 Use of at least one blue-light screening agent to preserve the amount of endogenous carotenoids in the skin, new blue- light screening agents, cosmetic compositions. OREAL (FR) 2013-08-21 EP claimed
WO-2012010554-A1 USE OF COMPOUNDS RESULTING FROM A SUGAR POLYOL OR FROM A DEHYDROGENATED SUGAR POLYOL DERIVATIVE AS A UV-SCREENING AGENT; ANTISUN COMPOSITIONS CONTAINING SAME; AND NOVEL COMPOUNDS L'OREAL (FR) 2012-01-26 WO claimed
US-7534421-B2 s-Triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof L'OREAL (FR) 2009-05-19 US claimed
US-20090074820-A1 AMINOARYLVINYL-S-TRIAZINE COMPOUNDS AND USES THEREOF L'OREAL (FR) 2009-03-19 US claimed
US-20050008588-A1 Aminoarylvinyl-s-triazine compounds and uses thereof L'OREAL (FR) 2005-01-13 US claimed
US-20040258636-A1 Novel s-triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof SOCIETE L'OREAL S.A. (FR) 2004-12-23 US claimed
EP-1466908-A1 S-tiazin-derivatives having at least one grafted para-aminobenzalmalonic acid salt and sun screening preparations comprising those derivatives L'OREAL (FR) 2004-10-13 EP claimed
CN-114746064-B Dual phase sunscreen composition 莱雅公司 2025-05-06 CN disclosed
CN-114760974-B Powdery cosmetic composition 莱雅公司 2025-04-29 CN disclosed
CN-119677494-A Flavored composition comprising at least one sulfur-containing antioxidant compound, at least one organic UV screening agent and at least one flavoring substance 莱雅公司 2025-03-21 CN disclosed
CN-119139159-A Anti-acne sunscreen composition, preparation method of anti-acne sunscreen composition and use of anti-acne sunscreen composition 欧莱雅 2024-12-17 CN disclosed
CN-114983866-B Reticular macromolecule sun-proof film cosmetic composition 广州科创材料科技有限公司 2024-09-13 CN disclosed
CN-113840592-B Waterproof cosmetic composition comprising light green clay and active ingredient derived from probiotics 欧莱雅 2024-09-13 CN disclosed
EP-1466908-A1 S-tiazin-derivatives having at least one grafted para-aminobenzalmalonic acid salt and sun screening preparations comprising those derivatives L'OREAL (FR) 2004-10-13 EP disclosed
US-6517742-B1 2-(butyl 4'-ylaminobenzoate)-4,6-bis((1,3,3,3-tetramethyl-1 -((trimethylsilyl)oxy)disiloxanyl)propyl-3-ylamino)-s-triazine; s-triazine derivatives substituted by at least one silicone group; from cyanuric chloride L'OREAL (FR) 2003-02-11 US disclosed
US-6172232-B1 Light stabilizers based on sterically hindered amines CLARIANT GMBH (DE) 2001-01-09 US disclosed
EP-0841341-B1 Sunscreen agents, and cosmetic compositions containing them OREAL (FR) 1999-04-07 EP disclosed
EP-0841341-A1 Sunscreen agents, and cosmetic compositions containing them L'OREAL (FR) 1998-05-13 EP disclosed
EP-0841341-A1 Sunscreen agents, and cosmetic compositions containing them L'OREAL (FR) 1998-05-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050008588-A1 Aminoarylvinyl-s-triazine compounds and uses thereof TYR, AAAS, ALAD MAPT 910/4885TDP1 2815/4885TSHR 1802/4885
US-20040258636-A1 Novel s-triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof TYR, KRT18, TST MAPT 1270/4885TDP1 1661/4885TSHR 4124/4885
US-20090074820-A1 AMINOARYLVINYL-S-TRIAZINE COMPOUNDS AND USES THEREOF TYR, AAAS, ALAD MAPT 874/4885TDP1 2786/4885TSHR 1736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.