Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.72 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.65 |
| ▸ | HTR3B | O95264 | 1/20 | 0.65 |
| ▸ | HTR3A | P46098 | 1/20 | 0.65 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.65 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 2/20 | 0.52 |
| ▸ | NOS2 | P35228 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656959 | 1.00 | NOS3 (0.72) | NOS3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4334880 | 1.00 | NOS3 (0.72) | NOS3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL13628631 | 0.87 | NOS3 (0.56) | NOS3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5112456 | 0.86 | NOS3 (0.72) | NOS3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL24105687 | 0.80 | NOS3 (0.64) | NOS3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL10513756 | 0.79 | NOS3 (0.63) | NOS3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4099711 | 0.79 | HTR3E (1.00) | NOS3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL15323278 | 0.79 | NOS3 (0.62) | NOS3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL15323282 | 0.79 | NOS3 (0.62) | NOS3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL24105688 | 0.77 | ESR2 (0.61) | NOS3HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612245-B2 | converting 1,3-butadiene to cis-2-butene in presence of a hydrogenation catalyst mixture containing iron octanoate, triethylaluminium, 2,3-bis(2,6-dimethylphenylimino)butane; catalyst selectivity | INSTITUT FRANCAIS DU PETROLE (FR) | 2009-11-03 | — | — | US | disclosed |
| US-20060129010-A1 | Method for selective hydrogenation of polyunsaturated compounds into monounsaturated compounds using a homogeneous catalyst | INSTITUTE FRANCAIS DU PETROLE (FR) | 2006-06-15 | — | — | US | disclosed |
| US-6444831-B2 | A MONOOLEFINIC COMPOUND IS ADDED TO A FATTY SUBSTANCE THAT COMPRISES TWO CONJUGATED OR UNCONJUGATED ETHYELNE BONDS IN PRESENCE OF A CATALYTIC SYSTEM CONTAINING IRON COMPOUNDS, A REDUCING AGENT, A LIGAND WHICH CONTAINS NITROGEN, ARSANIC ETC | INSTITUT FRANCAIS DU PETROLE (FR) | 2002-09-03 | — | — | US | disclosed |
| US-20010005758-A1 | Process for the codimerization of polyunsaturated fatty substances and olefins by iron complexes | INSTITUT FRANCAIS DE PETROLE (FR) | 2001-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060129010-A1 | Method for selective hydrogenation of polyunsaturated compounds into monounsaturated compounds using a homogeneous catalyst | PLA2G5, PLA2G2C, ELOVL6 | NOS3 1607/4885HTR3E 4289/4885HTR3B 2012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.