Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 4/20 | 1.00 |
| ▸ | HTR3B | O95264 | 4/20 | 1.00 |
| ▸ | HTR3A | P46098 | 4/20 | 1.00 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 1.00 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 1.00 |
| ▸ | NOS3 | P29474 | 4/20 | 0.76 |
| ▸ | ACR | P10323 | 2/20 | 0.69 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.68 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.68 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | NOS1 | P29475 | 2/20 | 0.59 |
| ▸ | NOS2 | P35228 | 2/20 | 0.59 |
| ▸ | FURIN | P09958 | 2/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.58 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.58 |
| ▸ | PLAU | P00749 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5635577 | 0.98 | HTR3E (0.96) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5423613 | 0.81 | NOS3 (0.68) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL4334877 | 0.79 | NOS3 (0.72) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL4334880 | 0.79 | NOS3 (0.72) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL10656959 | 0.79 | NOS3 (0.72) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5112456 | 0.79 | NOS3 (0.72) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL10513756 | 0.77 | NOS3 (0.63) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6618176 | 0.77 | HTR3E (0.66) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6138149 | 0.77 | HTR3E (0.62) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL4099965 | 0.77 | ADRA2A (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407720-A | A kind of catalysis of iodine thiocarbamide desulfurization preparation replaces the synthetic method of guanidine | XIAN MODERN CHEMISTRY RES INST | 2019-11-05 | — | — | CN | disclosed |
| CN-110156641-A | A kind of synthetic method replacing guanidine | 西安近代化学研究所 | 2019-08-23 | — | — | CN | disclosed |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| EP-1799684-A2 | LACTAM COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006041773-A2 | LACTAM COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-04-20 | — | — | WO | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1228058-A4 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2003-02-12 | — | — | EP | disclosed |
| EP-1228058-A1 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dongbu Hannong Chemical Co., Ltd. (KR) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001029023-A1 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2001-04-26 | — | — | WO | disclosed |
| EP-0337734-B1 | Heat-developable diazo copying material | FUJI PHOTO FILM CO LTD (JP) | 1995-03-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | KRT18, INMT, INHA | HTR3E 755/4885HTR3B 795/4885HTR3A 326/4885 |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | KRT18, KIT, PRDM7 | HTR3E 2678/4885HTR3B 2709/4885HTR3A 2555/4885 |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | KRT18, INHA, H1-5 | HTR3E 2522/4885HTR3B 2697/4885HTR3A 2631/4885 |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | BHMT, KRT18, INMT | HTR3E 2040/4885HTR3B 1371/4885HTR3A 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.